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Now showing items 1 - 7 of 7

  • Environmentally friendly procedure for in-situ coating of regenerated cellulose fibres with silver nanoparticles

    Pivec, Tanja   Hribernik, Silvo   Kolar, Mitja   Kleinschek, Karin Stana  

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  • Polysaccharide Based Wound Care Materials

    Maver, Tina   Maver, Uros   Pivec, Tanja   Kurecic, Manja   Persin, Zdenka   Kleinschek, Karin Stana  

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  • Emerging Techniques in the Preparation of Wound Care Products

    Maver, Tina   Maver, Uros   Pivec, Tanja   Kurecic, Manja   Persin, Zdenka   Kleinschek, Karin Stana  

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  • Modification of cellulose non-woven substrates for preparation of modern wound dressings

    Pivec, Tanja   Persin, Zdenka   Kolar, Mitja   Maver, Tina   Dobaj, Andreja   Vesel, Alenka   Maver, Uros   Stana-Kleinschek, Karin  

    Different ways are presented of modifying cellulosic non-woven substrates, which can serve as potential wound dressings with satisfactory antimicrobial and hydrophilic properties. For safe attachment of silver particles without a measurable release from the used materials, a sol-gel derived process was used. Alkaline and oxygen plasma treatments were used to improve the hydrophilicity of the materials. Their efficiency was determined by measuring contact angles and water retention values. Scanning electron microscopy (SEM) was used for determination of sample morphology prior to and after treatment. The efficiency of silver attachment and activity was evaluated by invitro release studies and antimicrobial tests. Atomic force microscopy (AFM) and SEM, combined with dynamic light scattering, were used for determination of silver particle size. Additionally, we evaluated the influence of treatment on technological parameters, important for application performance, i.e. mechanical properties and air permeability.
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  • Novel cellulose based materials for safe and efficient wound treatment.

    Persin, Zdenka   Maver, Uros   Pivec, Tanja   Maver, Tina   Vesel, Alenka   Mozetic, Miran   Stana-Kleinschek, Karin  

    The present study aims at achieving effects of improved hydrophilicity and microorganism inhibition, which are rarely simultaneously present in wound dressings. Viscose fibers in their non-woven form were modified using two different pathways. Effects of a two-step procedure, i.e. alkaline or oxygen plasma treatment followed by the attachment of silver chloride nanoparticles were compared to a one-step procedure, i.e. ammonium plasma treatment, which results in both desired material characteristics simultaneously. The surface properties of untreated and differently modified cellulose samples were analyzed by X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), in vitro silver release, and hydrophilicity measurements. The treatment effect on antimicrobial activity was determined by the AATCC 100-1999 standard test. In light of the introduced wound dressing preparation procedures and the desired wound dressing characteristics, the effectiveness of the used procedures was evaluated. Antimicrobial activity was proven against all Gram negative bacteria, while the Gram positive bacteria survive the as-prepared samples. Hydrophilicity was proven to be excellent using both preparation procedures. The mentioned results prove the potential of the used procedures and encourage future developments toward the clinical proof of concept. Copyright =C2=A9 2013 Elsevier Ltd. All rights reserved.
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  • Active Substances for Acceleration of Wound Healing

    Maver, Tina   Maver, Uros   Pivec, Tanja   Kurecic, Manja   Persin, Zdenka   Kleinschek, Karin Stana  

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  • Advanced Wound Care

    Maver, Tina   Maver, Uros   Pivec, Tanja   Kurecic, Manja   Persin, Zdenka   Kleinschek, Karin Stana  

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