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Now showing items 97 - 112 of 2468

  • Ward: An Exploratory Study of an Affective Sociotechnical Framework for Addressing Medical Errors

    Lee, W.   Winchester, W. W.   Smith-Jackson, T. L.  

    Affective states influence judgment, motivation, risk perceptions, and sense of well-being. Clinicians constantly struggle with negative affective states due to the nature of their work. We propose our framework, the Wearable Avatar Risk Display (WARD), to investigate medical errors from the perspective of affective states' influence. WARD is a dynamic and multimodal mobile affective system that aims for delivering information meaningfully and humanely to clinicians according to their affective states. WARD originates from sociotechnical systems theory and serves two purposes: (1) To guide the development of a test bed of avatars with lifelike behaviors (affective avatars) and (2) To investigate the interplay of clinicians' affects, risk perceptions, and decision-making ability in a healthcare setting. We recently piloted a small exploratory study using Mood Induction Procedures (MIPs), Iowa Gambling Task, and affective avatars to investigate participants' decision-making pattern. Our results indicated that participants did not benefit from our avatars currently. However, correlations analysis and suggestions from participants revealed that there is potential for affective avatars in critical or emergency situations.
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  • Resilient modulus of cohesive soils and the effect of freeze-thaw

    Lee, W.   Bohra, N. C.   Altschaeffl, A. G.   White, T. D.  

    The stress at 1%strain in the unconfined compression test (Su1.0%) was found to be a good indicator of the resilient modulus (MR), and an empirical relationship between MR and Su1.0% was obtained. Closed-system freeze-thaw tests were also performed and the effect of freeze-thaw on the resilient modulus was studied. There is a negligible effect of freeze-thaw, without ice lens formation, for soils having values of Su1.0% less than 8 psi (55 kPa), while the effect of freeze-thaw increases as the value of Su1.0% increases. The resilient modulus of frozen cohesive soil is independent of the repeated deviator stress.
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  • Functional Transfer of Pronator Quadratus Free Flap for Thenar Muscle Loss

    Lee, W.   Idler, Richard  

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  • Coupling constant and quark-loop expansion for corrections to the valence approximation

    Lee, W.   Weingarten, D.  

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  • Factor Xa inhibits HMGB1-induced septic responses in human umbilical vein endothelial cells and in mice

    Lee, W.   Ku, S.-K.   Bae, J.-S.  

    Nuclear DNA-binding protein high mobility group box 1 (HMGB1) acts as a late mediator of severe vascular inflammatory conditions, such as sepsis. Activated factor X (FXa) is an important player in the coagulation cascade responsible for thrombin generation, and it influences cell signalling in various cell types by activating protease-activated receptors (PARs). However, the effect of FXa on HMGB1-induced inflammatory response has not been studied. First, we addressed this issue by monitoring the effects of post-treatment with FXa on lipopolysaccharide (LPS)- and cecal ligation and puncture (CLP)-mediated release of HMGB1 and HMGB1-mediated regulation of pro-inflammatory responses in human umbilical vein endothelial cells (HUVECs) and septic mice. Post-treatment with FXa was found to suppress LPS-mediated release of HMGB1 and HMGB1-mediated cytoskeletal rearrangements. FXa also inhibited HMGB1-mediated hyperpermeability and leukocyte migration in septic mice. In addition, FXa inhibited the production of tumour necrosis factor-a and interleukin (IL)-1 beta. FXa also facilitated the downregulation of CLP-induced release of HMGB1, production of IL-6, and mortality. Collectively, these results suggest that FXa may be regarded as a candidate therapeutic agent for treating vascular inflammatory diseases by inhibiting the HMGB1 signalling pathway.
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  • Correction to “Distributed Parametric Resonator: A Passive CMOS Frequency Divider” [Sep 10 1834-1844]

    Lee, W.   Afshari, E.  

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  • Baryonic Force for Accelerated Cosmic Expansion and Generalized U1b Gauge Symmetry in Particle-Cosmology

    Khan, Mehbub   Hao, Yun   Hsu, Jong-Ping   Gwak, B.   Kang, G.   Kim, C.   Kim, H.-C.   Lee, C.-H.   Lee, J.   Lee, S.   Lee, W.  

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  • Entropy in Spacetime and Topological Hair

    Hyun, Young-Hwan   Kim, Yoonbai   Gwak, B.   Kang, G.   Kim, C.   Kim, H.-C.   Lee, C.-H.   Lee, J.   Lee, S.   Lee, W.  

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  • Tunneling decay of self-gravitating vortices

    Dupuis, Éric   Gobeil, Yan   Lee, Bum-Hoon   Lee, Wonwoo   MacKenzie, Richard   Paranjape, Manu B.   Yajnik, Urjit A.   Yeom, Dong-han   Gwak, B.   Kang, G.   Kim, C.   Kim, H.-C.   Lee, C.-H.   Lee, J.   Lee, S.   Lee, W.  

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  • Never seen before? Opisthorchiasis and Clonorchiasis

    Dietrich, Christoph   Atkinson, Nathan   Lee, W.   Kling, Kerstin   Neumayr, Andreas   Braden, Barbara   Richter, Joachim   Akpata, Robert   Southisavath, Phonesavanh   Schreiber-Dietrich, Dagmar   Dong, Yi  

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  • Forbidden Channels and SIMP Dark Matter

    Choi, Soo-Min   Kang, Yoo-Jin   Lee, Hyun Min   Gwak, B.   Kang, G.   Kim, C.   Kim, H.-C.   Lee, C.-H.   Lee, J.   Lee, S.   Lee, W.  

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  • Universal relations with fermionic dark matter

    Krut, A.   Argüelles, C. R.   Rueda, J. A.   Ruffini, R.   Gwak, B.   Kang, G.   Kim, C.   Kim, H.-C.   Lee, C.-H.   Lee, J.   Lee, S.   Lee, W.  

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  • Searches for magnetic monopoles with IceCube

    Pollmann, Anna   Gwak, B.   Kang, G.   Kim, C.   Kim, H.-C.   Lee, C.-H.   Lee, J.   Lee, S.   Lee, W.  

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  • Stability Analysis of Bulk Viscous Cosmology

    Sharif, M.   Mumtaz, Saadia   Gwak, B.   Kang, G.   Kim, C.   Kim, H.-C.   Lee, C.-H.   Lee, J.   Lee, S.   Lee, W.  

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  • Lithium augmentation in treatment-refractory unipolar depression

    Lee, W.   Cleare, A.  

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  • The Architectural Heritage of the Roanoke Valleyby W. L. Whitwell; Lee W. Winborne

    Review by: Dell Upton  

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