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    An injection molding machine includes a stationary platen and a moving platen mounted on a machine base, and a rotary apparatus for rotatably supporting a center mold section. The rotary apparatus includes a carriage body including a carriage upper portion supported by first and second carriage rails, and a carriage lower portion extending downward from the carriage upper portion laterally intermediate the first and second carriage rails. The rotary apparatus further includes a rotary table mounted atop the carriage body for rotatably supporting the center mold section. The rotary table is mounted to the carriage body by a rotary table bearing having a combination of bearing elements to bear axial, rotational, and moment loads. The machine further includes a plurality of tie bars extending between the moving platen and the stationary platen. The tie bars are free from engagement by the rotary apparatus.
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    An injection molding machine includes a base, a stationary platen fixed to the base for holding a first mold section, and a moving platen for holding a second mold section. The moving platen is slidably supported on a platen slide surface fixed to the base and moveable along a machine axis between a mold closed position, in which the moving platen is drawn towards the stationary platen, and a maximum daylight position, in which the moveable platen is spaced axially apart from the stationary platen by a platen opening. The machine further includes a carriage support structure slidably supporting a stack mold carriage for holding a mold center section. The stack mold carriage is translatable parallel to the machine axis between a carriage advanced position and a carriage retracted position spaced axially apart from the carriage advanced position by a carriage stroke length. The carriage support structure includes a pair of beams removably fixed relative to the base, the beams extending parallel to the machine axis and spaced apart from each other by a lateral spacing, each beam having a beam length that is less than the platen opening and greater than the carriage stroke length.
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    This invention provides for a solid, particulate insecticidal formulation in the form of a granule, a bait or a tablet for mechanical incorporation into or onto soil comprising a volatile insecticidal active ingredient that is microencapsulated and combined with a bulking agent and a disintegrating agent. The solid particulate formulation is characterized in that the volatile insecticide is selected from insecticidal active ingredients having: (a) a vapour pressure at 25°C in the range from about 1 mPa to about 1,000 mPa; and (b) a water solubility at 25°C less than about 100 mg/Litre.
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    A platen apparatus for supporting a mold portion in an injection molding machine includes a platen body and a mold mounting face adjacent a front of the platen body for supporting a mold half. The mold mounting face includes a rotary central surface that is rotatable about an axis relative to the platen body and a fixed peripheral surface that is fixed relative to the platen body. The peripheral surface is disposed about a periphery of the central surface. The central surface and the peripheral surface are alignable in a common vertical plane.
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  • Coaxial Feed Pyramidal Horn Antenna with High Efficiency

    Kumar, Hemant   Kumar, Girish  

    In this paper, a short pyramidal horn antenna with coaxial feed has been designed and fabricated with 52% bandwidth, which covers CDMA and GSM 900 bands. The total length of the antenna including coaxial feed is approximately 0.85 lambda at the lowest usable frequency. The effect of coaxial probe length, probe radius, and its location from the short wall of the waveguide on the resonance frequency, impedance matching, and bandwidth of the horn antenna have been analysed using CST Microwave studio software. Also, parametric analyses have been done by varying the horn length and aperture dimensions to study radiation characteristics of the horn antenna. The horn length has been optimized to obtain maximum efficiency for a fixed aperture. Simulation results show that as the frequency increases from 700 to 1130 MHz, the gain monotonically increases from 8.4 to 12.6 dBi with maximum efficiency of 80% at 850 MHz and it varies between 72% and 80% over this band. The pyramidal horn antenna has been fabricated and measured results are in good agreement with the simulated results.
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  • Monopulse Comparators [Applicaton Notes]

    Kumar, Hemant   Kumar, Girish  

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  • Commercialising innovations from the informal economy

    Sharma, Gautam   Kumar, Hemant  

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  • Treatment of Lignite Mine Water with Lignite Fly Ash and Its Zeolite

    Prasad, Bably   Kumar, Hemant  

    As expected, a zeolite formed from lignite fly ash proved to be far more effective in treating the water from the Neyvelli lignite mines than the fly ash itself. Treatment of mine water at different doses with both materials revealed that the zeolite increased the pH from 2.73 to 8.58 and removed most of the hardness, including the Ca and Mg hardness, as well as the acidity from the mine water. In contrast, the fly ash increased the hardness, Ca, Mg, and sulphate in the mine water. The fly ash was partially effective in removing metals like Mn, Ni, Zn, and Cr. In contrast, increased dosing of lignite fly ash zeolite removed 98.6% of the Mn, 99.94% of the Fe, 96.35% of the Ni, 99.30% of the Cu, 19.15% of the Cd, and 100% of the Zn, Pb, and Cr from lignite mine water. The surface of the lignite fly ash particles were initially covered with loosely attached metals that were released in the acidic water, though due to its alkaline nature, it did partially remove the metals from the mine water.
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  • TRPV4: a Sensor for Homeostasis and Pathological Events in the CNS

    Kumar, Hemant   Lee, Soo-Hong   Kim, Kyoung-Tae   Zeng, Xiang   Han, Inbo  

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  • Crystal Structure of a ligand-bound LacY-Nanobody Complex.

    Kumar, Hemant   Finer-Moore, Janet S   Jiang, Xiaoxu   Smirnova, Irina   Kasho, Vladimir   Pardon, Els   Steyaert, Jan   Kaback, H Ronald   Stroud, Robert M  

    The lactose permease of Escherichia coli (LacY), a dynamic polytopic membrane transport protein, catalyzes galactoside/H+ symport and operates by an alternating access mechanism that exhibits multiple conformations, the distribution of which is altered by sugar-binding. Camelid nanobodies were made against a double-mutant Gly46 Trp/Gly262 Trp (LacYWW) that produces an outward-open conformation, as opposed to the cytoplasmic open-state crystal structure of WT LacY. Nanobody 9047 (Nb9047) stabilizes WT LacY in a periplasmic-open conformation. Here, we describe the X-ray crystal structure of a complex between LacYWW, the high-affinity substrate analog 4-nitrophenyl-alpha-d-galactoside (NPG), and Nb9047 at 3-A resolution. The present crystal structure demonstrates that Nb9047 binds to the periplasmic face of LacY, primarily to the C-terminal six-helical bundle, while a flexible loop of the Nb forms a bridge between the N- and C-terminal halves of LacY across the periplasmic vestibule. The bound Nb partially covers the vestibule, yet does not affect the on-rates or off-rates for the substrate binding to LacYWW, which implicates dynamic flexibility of the Nb-LacYWW complex. Nb9047-binding neither changes the overall structure of LacYWW with bound NPG, nor the positions of side chains comprising the galactoside-binding site. The current NPG-bound structure exhibits a more occluded periplasmic vestibule than seen in a previous structure of a (different Nb) apo-LacYWW/Nb9039 complex that we argue is caused by sugar-binding, with major differences located at the periplasmic ends of transmembrane helices in the N-terminal half of LacY.=20
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  • Phase Transition in Monolayer Water Confined in Janus Nanopore

    Kumar, Hemant   Dasgupta, Chandan   Maiti, Prabal K.  

    The ubiquitous nature of water invariably leads to a variety of physical scenarios that can result in many intriguing properties. We investigate the thermodynamics and associated phase transitions for a water monolayer confined within a quasi-two-dimensional nanopore. An asymmetric nanopore constructed by combining a hydrophilic (hexagonal boron nitride) sheet and a hydrophobic (graphene) sheet leads to an ordered water structure at much higher temperatures compared to a symmetric hydrophobic nano pore consisting of two graphene sheets. The discontinuous change in the thermodynamic quantities, potential energy (U), and entropy (S) of confined water molecules computed from the all-atom molecular dynamics simulation trajectories, uncovers a first-order phase transition in the temperature range of T =3D 320-330 K. Structural analysis reveals that water molecules undergo a disorder-to-order phase transformation in this temperature range with a 4-fold symmetric phase persisting at lower temperatures. Our findings predict a novel confinement system which has the melting transition for monolayer water above the room temperature, and provide a microscopic understanding which will have important implications for other nanofludic systems as well.
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  • Lactose Permease: Mechanism through Structures

    Kumar, Hemant   Kaback, H. Ronald   Stroud, Robert M.  

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  • Micromechanical characterisation of Indian rail steel

    Srivastava, Jay Prakash   Kumar Sarkar, Prabir   Gautam, Abhinav   Yadav, Rajkumar   Kumar, Hemant  

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  • Reconstructing the evolutionary history of F420-dependent dehydrogenases

    Mascotti, M. Laura   Kumar, Hemant   Nguyen, Quoc-Thai   Ayub, Maximiliano Juri   Fraaije, Marco W.  

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  • Conversion of Furans by Baeyer-Villiger Monooxygenases

    Kumar, Hemant   Fraaije, Marco W.  

    Various furans are considered as valuable platform chemicals as they can be derived from plant biomass. Yet, for their exploitation, follow-up chemistry is required. Here we demonstrate that Baeyer-Villiger monooxygenases (BVMOs) can be used as biocatalysts for the selective oxidation of several furans, including 5-(hydroxymethyl) furfural (HMF) and furfural. A total of 15 different BVMOs were tested for their activity on furfural, which revealed that most of the biocatalysts were active on this aromatic aldehyde. Phenylacetone monooxygenase (PAMO) and a mutant thereof (PAMO(M446G)) were selected for studying their biocatalytic potential in converting furfural and some other furans. While BVMOs are usually known to form an ester or lactone as a 'normal' product by inserting an oxygen atom adjacent to the carbonyl carbon of the substrate, our results reveal that both biocatalysts produce furanoid acids as the main product from the corresponding aldehydes. Altogether, our study shows that BVMOs can be employed for the selective oxidation of furans.
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  • Tunable Magnetism and Transport Properties in Nitride MXenes

    Kumar, Hemant   Frey, Nathan C.   Dong, Liang   Anasori, Babak   Gogotsi, Yury   Shenoy, Vivek B.  

    Two-dimensional materials with intrinsic and robust ferromagnetism and half-metallicity are of great interest to explore the exciting physics and applications of nanoscale spintronic devices, but no such materials have been experimentally realized. In this study, we predict several M2NTx nitride MXene structures that display these characteristics based on a comprehensive study using a crystal field theory model and first-principles simulations. We demonstrate intrinsic ferromagnetism in Mn2Tx with different surface terminations (T =3D O, OH, and F), as well as in Ti2NO2 and Cr2NO2. High magnetic moments (up to 9 mu(B) per unit cell), high Curie temperatures (1877 to 566 K), robust ferromagnetism, and intrinsic half-metallic transport behavior of these MXenes suggest that they are promising candidates for spintronic applications, which should stimulate interest in their synthesis.
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