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Now showing items 1 - 16 of 391

  • MEMS device with over-travel stop structure and method of fabrication

    A MEMS device comprises a substrate, a proof mass spaced apart from a surface of the substrate, and an over-travel stop structure. The over-travel stop structure includes a lateral stop structure and a cap coupled to the lateral stop structure. The MEMS device is fabricated to include relatively small gap sections and relatively large gap regions separating the lateral stop structure from the proof mass. The larger gap regions are covered by the cap and the smaller gap sections are exposed from the gap. During fabrication, removal of particles from the smaller gap sections is facilitated by their exposure from the cap and removal of particles from the larger gap regions underlying the cap is facilitated by their larger size. The lateral stop structure may be cross-shaped to limit deflection of the proof mass along two in-plane axes. The cap limits deflection of the proof mass along an out-of-plane axis.
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  • Multi-axis inertial sensor with dual mass and integrated damping structure

    An inertial sensor includes first and second movable elements suspended from a substrate and interconnected by a beam. The second movable element is positioned laterally adjacent to the first movable element, and each of the movable elements has a mass that is asymmetric relative to a rotational axis. A first spring system couples the first movable element to the substrate and a second spring system couples the second movable element to the substrate. The spring systems and the beam enable the movable elements to move together in response to force imposed upon the movable elements. In particular, the first and second movable elements can undergo in-plane torsion motion in response to force, such as acceleration, imposed in a sense direction. Additionally, damping structures may be integrated into the first and second movable elements to effectively increase a damping ratio of the device resulting from the in-plane torsion motion.
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  • Apparatus and method for controlling charging and discharging of batteries

    An apparatus is electrically connected to a battery unit consisting of multiple batteries, an energy conversion system, and power-driven equipment. The apparatus sets number requirements of batteries to be connected to a discharge unit and a charge unit of the battery unit. When the power-driven equipment is started, the apparatus receives an open-circuit voltage of each battery detected by a sensor connected to the battery, and establishes connections of the batteries with the discharge unit or the charge unit according to the open-circuit voltages of the batteries and the number requirements. During the discharge unit supplying power to the power-driven equipment and the energy conversion system charging the charge unit, the apparatus monitors variations of the open-circuit voltages of the batteries, and switches the connections of batteries with the discharge unit or the charge unit according to associations between open-circuit voltages, cut-off discharge voltages, and nominal voltages of the batteries.
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  • Target models and waveform design for detection in MIMO radar

    Jun Tang   Jun Luo   Bo Tang   JinSong Du  

    In this paper, we propose a general target model for multiple-input multiple-output (MIMO) radar. Two types of targets are presented. For each type of target, we develop a corresponding optimum waveform designing method to optimize detection performance. Based on Chernoff-Stein lemma, we use relative entropy as the performance measure. We show that the optimum waveform designing method can obtain better detection performance than traditional orthogonal waveform designing method.
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  • Co-expression of EGFR and CK5/6 in primary squamous cell carcinoma of the breast

    Jin Wang   Xinke Zhang   Jiehua He   Mingtian Yang   Jun Tang   Xing Li…  

    Primary squamous cell carcinoma of the breast (PSCCB) is an extremely rare breast tumor lacking hormone receptors and HER2 expression. However, in comparison with triple-negative invasive ductal carcinoma (TN-IDC), little is known about the PSCCB. Twenty-nine patients with PSCCB in Sun Yat-sen University Cancer Center from 1995 to 2010 were recruited in this study, along with 681 cases of TN-IDC during the same period. The clinicopathologic features and prognosis of PSCCB compared to TN-IDC were assessed. Furthermore, biomarkers of EGFR, CK5/6, E-cadherin, VEGF, TOPII, and p53 were immunostained to investigate the prognostic determinant of PSCCB. Patients with PSCCB were older than those with TN-IDC (P = 0.009) and presented with lower lymph node involvement (P = 0.015). There was no difference in overall survival (OS) between PSCCB and TN-IDC. However, the disease-free survival (DFS) of PSCCB was poorer than that of TN-IDC (P = 0.007). Multivariate analysis revealed that combined over-expression of EGFR and CK5/6 was the only independent prognostic factor for OS of PSCCB (HR 6.08, 95 % CI 1.33-27.85, P = 0.020) and associated with lymphatic metastasis (P = 0.023) and p53 expression (P = 0.013). Other predictors for poorer OS and DFS were lymphatic metastasis and stage III, which failed to show significance after multivariate analysis. Furthermore, platinum-based chemotherapy was identified to improve the OS of PSCCB with EGFR + CK5/6+ (P = 0.027). The prognosis of PSCCB is poorer than that of TN-IDC. As the only independent prognostic factor for PSCCB, combined overexpression of EGFR and CK5/6 might be a potential indicator for the use of platinum-based chemotherapy.
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  • Fabrication of gold nanoparticle lines based on fracture induced patterning

    Jun Tang   S. Kolliopoulou   D. Tsoukalas  

    We present a low cost method for the selective deposition of gold nanoparticles from a gold colloid. We first introduce a process of maskless patterning on a photoresist layer. With this process, we have fabricated photoresist gratings with a period from 1 to 30 μm, using the fracture induced patterning technique. Then we have performed gold nanoparticle deposition on this patterned surface by a surface functionalization technique. For that purpose, silicon dioxide (SiO2) was deposited on the sample followed by a lift-off process. The remained SiO2 lines after the lift-off were functionalized with 2,3-aminopropyltrimethoxysilane (APTMS) for the selective deposition of the gold colloid. After the deposition, the gold nanoparticles are well organized on top of the SiO2 line patterns.
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  • Fabrication of gold nanoparticle lines based on fracture induced patterning

    Jun Tang   S. Kolliopoulou   D. Tsoukalas  

    We present a low cost method for the selective deposition of gold nanoparticles from a gold colloid. We first introduce a process of maskless patterning on a photoresist layer. With this process, we have fabricated photoresist gratings with a period from 1 to 30 mum, using the fracture induced patterning technique. Then we have performed gold nanoparticle deposition on this patterned surface by a surface functionalization technique. For that purpose, silicon dioxide (SiO 2) was deposited on the sample followed by a lift-off process. The remained SiO 2 lines after the lift-off were functionalized with 2,3-aminopropyltrimethoxysilane (APTMS) for the selective deposition of the gold colloid. After the deposition, the gold nanoparticles are well organized on top of the SiO 2 line patterns. [All rights reserved Elsevier].
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  • Interleaver address generation in turbo decoders for wireless communication systems

    Address generation for interleaving in a wireless communication system includes at least one input generation module to generate at least one input signal. A first address generator module and a second address generator module generate a first output address for interleaving and a second output address for interleaving. A selector module selects an address for interleaving from the first and the second output address based on predetermined criteria. At least one input translation module is receives an input signal and translate the received input signal to generate a nominal input signal based on a value of the received input signal. An address generation module generates an address for interleaving based on the nominal input signal.
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  • Interleaver address generation in turbo decoders for wireless communication systems

    Address generation for interleaving in a wireless communication system includes at least one input generation module to generate at least one input signal. A first address generator module and a second address generator module generate a first output address for interleaving and a second output address for interleaving. A selector module selects an address for interleaving from the first and the second output address based on predetermined criteria. At least one input translation module is receives an input signal and translate the received input signal to generate a nominal input signal based on a value of the received input signal. An address generation module generates an address for interleaving based on the nominal input signal.
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  • A directly strain measuring method for electroplated nickel micro-tensile test

    Jun Tang   Hong Wang   Rui Liu   Xueping Li   Zhenjie Zhang   Jinyuan Yao and Guifu Ding  

    In order to avoid the post-processing in micro-tensile tests, a directly strain measuring method is presented in this paper. The nickel tensile test specimen was electroplated in Watts solution under certain conditions. The measured Young’s modulus, ultimate tensile strength and elongation are 171.5 GPa, 2.18 GPa and 13.8%, respectively. By comparing these results to that obtained by the traditional method, this new approach has been proved reliable. Furthermore, the mean grain size of the nickel specimen measured by TEM images is about 160 nm with wide distribution. The XRD results show that nickel thin film in our experiment has no preferred orientation in the growth direction. The dimple rupture with small microvoids has been observed after the fracture of specimen.
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  • Minimum fluidisation velocities of burned oil sand particles

    Jun Tang   Xiaona Chen   Yongmin Zhang   Chunxi Lu   Zhiyuan Shen  

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  • p- and n-Type Ba8Ga16Ge30 studied by X-ray photoelectron spectroscopy

    Jun Tang   Ryotaro Kumashiro   Jing Ju   Zhaofei Li   Marcos A. Avila   Kouichirou Suekuni   Toshiro Takabatake   Fangzhun Guo   Keisuke Kobayashi   Katsumi Tanigaki  

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  • Ca2+spiral waves in a spatially discrete and random medium

    Jun Tang   Lijian Yang   Jun Ma   Ya Jia  

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  • Guillain-Barré Syndrome in Chinese Children: A Retrospective Analysis

    Jun Tang   Ying Dai   Mei Li   Min Cheng   Siqi Hong   Li Jiang   Fangcheng Cai   Min Zhong  

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  • Knowledge-based design of 7-azaindoles as selective B-Raf inhibitors

    Jun Tang   Toshihiro Hamajima   Masato Nakano   Hideyuki Sato   Scott H. Dickerson   Karen E. Lackey  

    The synthesis of a 7-azaindole series of novel, potent B-Raf kinase inhibitors using knowledge-based design was carried out. Compound 6h exhibits not only excellent potency in both the enzyme assay (IC50 = 2.5 nM) and the cellular assay (IC50 = 63 nM), but also has an outstanding selectivity profile against other kinases.
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  • Knowledge-based design of 7-azaindoles as selective B-Raf inhibitors

    Jun Tang   Toshihiro Hamajima   Masato Nakano   Hideyuki Sato   Scott H. Dickerson   Karen E. Lackey  

    The synthesis of a 7-azaindole series of novel, potent B-Raf kinase inhibitors using knowledge-based design was carried out. Compound 6h exhibits not only excellent potency in both the enzyme assay (IC50 = 2.5 nM) and the cellular assay (IC50 = 63 nM), but also has an outstanding selectivity profile against other kinases.
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