Creat membership Creat membership
Sign in

Forgot password?

  • Forgot password?
    Sign Up
  • Confirm
    Sign In
home > search

Now showing items 1 - 16 of 65

  • Severe Hypocalcemia in a Patient with Recurrent Chondrosarcoma

    Eun, Jung Nam   Choi, Yoo Duk   Lee, Jeong Ho   Jeong, Yun Ah   Yoon, Jee Hee   Kim, Hee Kyung   Kang, Ho-Cheol  

    Hypocalcemia is relatively uncommon paraneoplastic syndrome. Only one case of hypocalcemia has been reported in a patient with chondrosarcoma. We herein report a case of a 32-year-old woman with metastatic chondrosarcoma with tetany. Her imaging findings revealed multiple calcific metastatic lesions in the lungs, pancreas, left atrium, and pulmonary vein. A laboratory examination showed hypocalcemia with no evidence of any other disease that could induce hypocalcemia. On the basis of the laboratory and clinical findings, we concluded the etiology of her severe hypocalcemia to be excessive calcium consumption by the tumor itself.
    Download Collect
  • Differentiation of angioimmunoblastic T-cell lymphoma from DRESS syndrome

    Jeong, Jiung   Sim, Da Woon   Yu, Ji Eun   Choi, Yoo Duk   Kim, Seul Kee   Yoon, Woong   Koh, Young-Il  

    Download Collect
  • Parathyroid Crisis Caused by a Large Parathyroid Adenoma

    Ma, Seong Kwon   Oh, Tai Ryeom   Choi, Yoo Duk   Kim, Soo Wan  

    Download Collect
  • Pleomorphic adenoma of the trachea.

    Sim, Da Woon   Oh, In Jae   Kim, Kyu Sik   Choi, Yoo Duk   Kwon, Yong Soo  

    Endobronchial pleomorphic adenoma is an extremely rare condition. A 32-year-old woman with exertional dyspnea and cough presented with a carinal mass on chest CT scan. The tumor was successfully removed by rigid bronchoscopy using argon plasma coagulation. Biopsy confirmed the diagnosis of pleomorphic adenoma. =20
    Download Collect
  • Castleman's disease presenting as a tracheal mass.

    Yu, Jin Yeong   Oh, In Jae   Kim, Kyu Sik   Kim, Yu Il   Lim, Sung Chul   Kim, Young Chul   Choi, Yoo Duk   Kwon, Yong Soo  

    Castleman's disease (CD) is a rare lymphoproliferative disorder of uncertain cause. The most common site of involvement is the mediastinum. Endotracheal CD is extremely rare. We report a case of unicentric, hyaline-vascular type CD presenting as an obstructive tracheal mass. The tumor was successfully managed by rigid bronchoscopy with argon plasma coagulation. There was no recurrence at the 2-month follow-up visit. Copyright =C2=A9 2014 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
    Download Collect
  • The Case vertical bar A 69-year-old-woman with polyuria

    Kang, Ji Hyoun   Choi, Yoo Duk   Kim, Chang Seong   Choi, Joon Seok   Bae, Eun Hui   Ma, Seong Kwon   Kim, Soo Wan  

    Download Collect
  • Erdheim Chester Disease (ECD): A Case Report

    Lee, Jin-Ho   Jung, Sung-Taek   Choi, Yoo Duk  

    Download Collect
  • TCL1 expression predicts overall survival in patients with mantle cell lymphoma.

    Shin, Su-Jin   Roh, Jin   Cha, Hee Jeong   Choi, Yoo Duk   Kim, Jin-Man   Min, Soo Kee   Kim, Ji Eun   Eom, Dae-Woon   Lee, Hojung   Kim, Hyun-Jung   Yoon, Dok Hyun   Suh, Cheolwon   Huh, Jooryung  

    OBJECTIVES: Mantle cell lymphoma (MCL) has a heterogeneous clinical course. Although most cases show a poor prognosis, a minority has an indolent course. It is difficult to identify indolent MCL cases prospectively. T-cell leukemia/lymphoma protein 1 (TCL1) is expressed by several B-cell lymphomas, including MCL. This study examined the expression of TCL1 and its prognostic relevance for MCL.; METHODS: Clinical data for 162 patients with MCL were collected. Of these, 144 cases with available tissues for tissue microarray construction and immunostaining were included in the analysis. TCL1 staining was quantified using the Nuclear Quant application with Pannoramic Viewer v. 1.14. High TCL1 expression was defined as moderate to strong nuclear and/or cytoplasmic staining in 40% or more of the cells.; RESULTS: High TCL1 expression was observed in 39 of 144 samples (27.1%). Patients with low TCL1 expression were more likely to present with blastoid/pleomorphic morphology (P =3D 0.010). Low TCL1 expression was associated with significantly shorter overall survival (OS, P =3D 0.006). Multivariate analysis identified low TCL1 expression (P =3D 0.003), high-risk MIPI (P =3D 0.027), and anemia (P =3D 0.018) as adverse prognostic factors.; CONCLUSIONS: Our study suggests that TCL1 expression profile may have a role in the prediction of overall outcome in patient with MCL and call for prospective studies. =C2=A9 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
    Download Collect
  • Prostate Cancer with Solitary Metastases to the Bilateral Testis

    Kim, Sun-Ouck   Choi, Yoo Duk   Jung, Seung Il   Oh, Kyung Jin   Im, Chang Min   Kang, Taek Won   Kwon, Dongdeuk   Park, Kwangsung   Ryu, Soo Bang  

    We present the case of an 81-year-old patient with testicular metastasis from prostate carcinoma. After the initial diagnosis of prostate cancer, he had an 8-year course of hormonal therapy and showed no clinical evidence of metastasis to other organs. Asymptomatic metastasis of prostate carcinoma to the testis is a rare clinical condition. We diagnosed his condition, based on histopathology following a subcapsular orchiectomy and transurethral resection of the prostate.
    Download Collect
  • Prostate Cancer with Solitary Metastases to the Bilateral Testis

    Kim, Sun-Ouck   Choi, Yoo Duk   Jung, Seung Il   Oh, Kyung Jin   Im, Chang Min   Kang, Taek Won   Kwon, Dongdeuk   Park, Kwangsung   Ryu, Soo Bang  

    Download Collect
  • Mesonephric Adenocarcinoma of the Uterine Corpus:A Case Report and Diagnostic Pitfall

    Kim, Sung Sun   Nam, Jong Hee   Kim, Ga-Eon   Choi, Yoo Duk   Choi, Chan   Park, Chang Soo  

    Mesonephric adenocarcinoma is a rare tumor type that is usually found in areas where the Wolffian duct was present during the fetal period. We report a case of mesonephric adenocarcinoma of the uterine corpus in a 66-year-old woman who presented with vaginal bleeding. Pelvic magnetic resonance imaging revealed a 2.7-cm-sized irregular thickening and enhancement of the uterine body. The diagnosis following endometrial curettage biopsy was endometrioid adenocarcinoma, and the patient underwent a total hysterectomy with bilateral salpingo-oophorectomy. The tumor was composed of small tubular and ductal components, and a retiform appearance was also observed in the deeper areas. The tumor cells were immunopositive for cytokeratin, vimentin, CD10 with a luminal staining pattern, PAX2, and PAX8, and immunonegative for estrogen receptor and progesterone receptor, which was consistent with tumor of mesonephric origin. Mesonephric neoplasms reveal relatively low-grade nuclear feature, characteristic immunoprofiles (immunonegative for ER and PR, and immunopositive for CD10, PAX2, PAX8, and GATA3), and unique tumor location (myometrium), whereas Mullerian neoplasms such as endometrial adenocarcinoma show various morphology, immunopositivity for ER and PR, and primarily endometrial location. As described above, an integration of the clinical features, morphologic characteristics, and immunohistochemical profiles is needed to make a diagnosis.
    Download Collect
  • Imaging Findings of Localized Lymphoid Hyperplasia of the Pancreas: a Case Report

    Kim, Jin Woong   Shin, Sang Soo   Heo, Suk Hee   Jeong, Yong Yeon   Kang, Heoung Keun   Choi, Yoo Duk  

    Download Collect
  • Thyroid Cartilage Metastasis from the Lung

    Lee, Joon Kyoo   Yoon, Tae Mi   Kim, Hee Dae   Lee, Sung Su   Lim, Sang Chul   Choi, Yoo Duk   Nam, Jong Hee  

    Download Collect
  • Endobronchial Schwannoma Treated by Rigid Bronchoscopy with Argon Plasma Coagulation

    Lee, Bo Ram   Choi, Yoo Duk   Kim, Yu Il   Lim, Sung Chul   Kwon, Yong Soo  

    Download Collect
  • NF-kappa B regulates Lef1 gene expression in chondrocytes

    Yun, Kangsun   Choi, Yoo Duk   Nam, Jong Hee   Park, Zeeyoung   Im, Sin-Hyeog  

    The relation of Wnt/beta-catenin signaling to osteoarthritis progression has been revealed with little information on the underlying molecular mechanism. In this study we found overexpression of Lef1 in cartilage tissue of osteoarthritic patients and elucidated molecular mechanism of NF-kappa B-mediated Lef1 gene regulation in chondrocytes. Treatment of IL-1 beta augmented Lef1 upregulation and nuclear translocation of NF-kappa B in chondrocytes. Under IL-1 beta signaling, treatment of NF-kappa B nuclear translocation inhibitor SN-50 reduced Lef1 expression. A conserved NF-kappa B-binding site between mouse and human was selected through bioinformatic analysis and mapped at the 14 kb upstream of Lef1 transcription initiation site. NF-KB binding to the site was confirmed by chromatin immunoprecipitation assay. Lef1 expression was synergistically upregulated by interactions of NF-KB with Lef1/beta-catenin in chondrocytes. Our results suggest a pivotal role of NF-KB in Lef1 expression in arthritic chondrocytes or cartilage degeneration. (c) 2007 Elsevier Inc. All rights reserved.
    Download Collect
  • Three cases of xanthogranulomatous epididymitis caused by E. coli.

    Kang, Taek Won   Lee, Kyung Hwa   Piao, Cheng Zhe   Yun, Ki Jung   Joo, Hee Jae   Park, Kwang Sung   Choi, Yoo Duk   Juhng, Sang Woo   Choi, Chan  

    Xanthogranulomatous epididymitis is an uncommon but benign process, characterized by tissue destruction and the accumulation of abundant foamy macrophages mixed with lymphocytes and plasma cells. The pathogens generally found to cause xanthogranulomatous inflammation have been Proteus and E. coli. We identified such a pathogen by sequencing divergent regions of 16S rRNA, followed by pathogen-specific-PCR using alr, ipaH, ial, and iuc primer pairs in DNA microdissected from an H&E stained slide. We report here three cases of xanthogranulomatous epididymitis caused by E. coli.
    Download Collect
1 2 3 4 5


If you have any feedback, Please follow the official account to submit feedback.

Turn on your phone and scan

Submit Feedback