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Now showing items 1 - 16 of 1736

  • A conversation with Professor Bo Zhang

    Zhang   Bo  

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  • Anti-vasa antibodies, and methods of production and use thereof

    Anti-VASA antibodies (mAbs), particularly humanized mAbs that specifically bind to VASA with high affinity, are disclosed. The amino acid sequences of the CDRs of the light chains and the heavy chains, as well as consensus sequences for these CDRs, of these anti-VASA mAbs are provided. The disclosure also provides nucleic acid molecules encoding the anti-VASA mAbs, expression vectors, host cells, methods for making the anti-VASA mAbs, and methods for expressing the anti-VASA mAbs. Finally, methods of using the anti-VASA mAbs to isolate and/or purify cells expressing VASA are disclosed.
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  • Anti-VASA antibodies, and methods of production and use thereof

    Anti-VASA antibodies (mAbs), particularly humanized mAbs that specifically bind to VASA with high affinity, are disclosed. The amino acid sequences of the CDRs of the light chains and the heavy chains, as well as consensus sequences for these CDRs, of these anti-VASA mAbs are provided. The disclosure also provides nucleic acid molecules encoding the anti-VASA mAbs, expression vectors, host cells, methods for making the anti-VASA mAbs, and methods for expressing the anti-VASA mAbs. Finally, methods of using the anti-VASA mAbs to isolate and/or purify cells expressing VASA are disclosed.
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  • Oral care implement and method of manufacturing an oral care implement

    A method of manufacturing an oral care implement comprising: (a) providing a body comprising a handle portion and a head portion, the head portion having a hole extending there through from a first side to a second side; (b) providing a layer of first material on the handle portion and the head portion to form a subassembly comprising a handle section, comprising the handle portion and a first portion of the layer of first material, and a head section, comprising the head portion and a second portion of the layer of first material; and (c) then injection molding a second material onto the head section to form one or more oral care elements of the second material on the head section and a member of the second material in the hole, which member is unitary with the one or more oral care elements.
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  • Method and apparatus for distortion correction in optical communication links

    In some embodiments, an apparatus includes an optical transmitter module that can be electrically coupled to an electrical serializer/deserializer and a controller. The optical transmitter module can include an electrical detector that can receive an in-band signal. The electrical detector can send to the controller a first power error signal and a second power error signal based on the in-band signal. The controller can send a correction control signal to the electrical serializer/deserializer based on the first power error signal and the second power error signal such that the electrical serializer/deserializer sends a pre-emphasized signal to the optical transmitter module based on the correction control signal. In such embodiments, the first power error signal, the second power signal and the correction control signal are out-of-band signals.
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  • Bidirectional MOS device and method for preparing the same

    A bidirectional Metal-Oxide-Semiconductor (MOS) device, including a P-type substrate, and an active region. The active region includes a drift region, a first MOS structure and a second MOS structure; the first MOS structure includes a first P-type body region, a first P+ contact region, a first N+ source region, a first metal electrode, and a first gate structure; the second MOS structure includes a second P-type body region, a second P+ contact region, a second N+ source region, a second metal electrode, and a second gate structure; and the drift region includes a dielectric slot, a first N-type layer, a second N-type layer, and an N-type region. The active region is disposed on the upper surface of the P-type substrate. The first MOS structure and the second MOS structure are symmetrically disposed on two ends of the upper layer of the drift region.
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  • Detection and compensation of power imbalances for a transmitter

    An optical device may include a transmitter to provide an optical signal via a set of channels and a modulator. The optical device may include two or more tributary modulators to modulate the set of channels with a training pattern. The optical device may include a set of optics to alter a first channel relative to a second channel of the set of channels. The optical device may include a detector to determine an optical power measurement of the optical signal after the first channel is altered relative to the second channel. The optical device may include a controller to generate a control signal to adjust a power balance associated with the optical signal based on the optical power measurement. The optical device may include a controller to provide the control signal to a tributary modulator to alter a modulation of the optical signal.
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  • Low-dropout regulator with dynamic pole tracking circuit for improved stability

    A low-dropout regulator, including: a dynamic pole tracking circuit having an active load, a voltage-to-current converter, a current amplifier, a bias circuit, a regulating transistor, a first feedback resistor, a second feedback resistor, and a first capacitor. The dynamic pole tracking circuit includes: a first PMOS, a second PMOS, a first resistor, and a second resistor. The voltage-to-current converter includes: a first NMOS, a second NMOS, a third NMOS, a fourth NMOS, a fifth NMOS, a sixth NMOS, a seventh NMOS, an eighth NMOS, a third PMOS, a fourth PMOS, a seventh PMOS, an eighth PMOS. The current amplifier includes: a fifth PMOS, a sixth PMOS, a ninth NMOS, a tenth NMOS, and a third resistor. The bias circuit includes: a ninth PMOS, a tenth PMOS, an eleventh PMOS, an eleventh NMOS, a twelfth NMOS, a thirteenth NMOS, and a fourth resistor.
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  • The Impact of New Features on Positioning Technology in LTE-A System

    Bo Zhang   Yuanfeng Du   Dongkai Yang  

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  • Phase alignment architecture for ultra high-speed data path

    A phase alignment architecture enhances the performance of communication systems. The architecture aligns a divided clock (e.g., in differential Inphase (I) and Quadrature (Q)) to a main clock, even at extremely high speeds, where skew variations of the divided clock are comparable to the main clock period. The improvement in phase alignment facilitates ultra high-speed communications.
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  • Minimizing polarization-dependent optical power for PM-M-QAM transmitters

    A system is configured to determine a first power level of a first signal output from a first modulator, and determine a second power level of a second signal output from a second modulator. The first signal may include a first optical signal associated with a particular polarization orientation, and the second signal may include a second optical signal associated with the particular polarization orientation. The system is configured to determine a relationship between the first power level and the second power level, and to set, based on the relationship between the first power level and the second power level, a reverse bias voltage associated with the first modulator, where the reverse bias voltage may be used to control the first power level of the first signal.
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  • Method of using alpha-amylase from Aspergillus clavatus for saccharification

    A fungal α-amylase is provided from Aspergillus clavatus (AcAmyl). AcAmyl has an optimal pH of 4.5 and is operable at 30-75° C., allowing the enzyme to be used in combination with a glucoamylase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the α-amylase or glucoamylase. AcAmyl also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DP1+DP2) compared to the products of saccharification catalyzed by an α-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.
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  • Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon

    Disclosed are nanostructured gold films which may be produced by solution-phase depositions of gold ions onto a variety of surfaces. The resulting plasmonic gold films are used for enhanced spectroscopic-based immunoassays in multiplexed microarray format with detection mechanisms based on either surface-enhanced Raman scattering or near-infrared fluorescence enhancement. The preparation of the films and subsequent modifications of the gold film surfaces afford increased sensitivity for various microarrays. The films are discontinuous, forming gold “islands.” Sensitivity, size, shape, and density of the nanoscopic gold islands comprising the discontinuous nanostructured gold film are controlled to enhance the intensity of Raman scattering and fluorescence in the near-infrared, allowing for improved measurements in clinical diagnostic or biomedical research applications.
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  • Method and device for displaying information flows in social network, and server

    The present disclosure relates to a method and a device for displaying information flows in a social network. The method includes judging whether pieces of target information with a number of pieces being greater than or equal to a set number exist in information flows posted within a set time period by a user of the social network, aggregating the pieces of target information into one or more target information groups according to a preset rule when the pieces of target information exist, and displaying the target information group.
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  • Multi-phase SMPS with load transient control and associated control method

    The present invention discloses a multi-phase switch-mode power supply (SMPS). The multi-phase SMPS may comprise a plurality of comparing circuits and a controller. Wherein each comparing circuit comprises a first input coupled to a threshold voltage, a second input coupled to a feedback signal of the output voltage, and an output configured to provide a load indication signal. The controller may have a plurality of inputs coupled to the outputs of the comparing circuit, and a plurality of outputs configured to provide control signals for driving a plurality of switches of the multi-phase SMPS. And the controller is configured to selectively turn on a plurality of the switches according to the load indication signals.
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  • Suggesting opt-out of notifications to users of a social networking system

    A social networking system notifies its users of different events and actions taking place inside the social networking system. To present notifications that are most likely to be of interest to the user, the social networking system observes the interactions of the user with notifications presented to the user and suggests an option to opt-out of notifications associated with a source based on the observed interactions. The option to opt-out of notifications associated with the source may be presented if the users interactions with the notifications presented are below a threshold. Notifications associated with a social group are presented to the user based on factors describing the group and the relation between the user and other users of the social group, for example, seniority of the user, size of the group, and the rate at which user actions associated with the group are received.
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