The present invention provides adipose-derived stem cells (ADSCs}, adipose-derived stem cell-enriched fractions (ADSC-EF} and adipose-derivedlattices, alone and combined with the ADSCs of the invention. In one aspect, the present invention provides an ADSC substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The ADSCs can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the ADSCs can be expanded and cultured to produce molecules such as hormones, and to provide conditioned culture media for supporting the gro$m(k) and expansion of other cell populations. In another aspect, the present invention provides a adipose-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue. The lattice can be used as a substrate to facilitate the growth and differentiation of cells, whether in vivo or in vitro, into anlagen or even mature tissues or structures.

The invention relates to a high resolution bathymetric sonar system and measuring method for measuring the physiognomy of the seabed. The system contains underwater electronic section which is installed in the underwater carrier, two sonar arrays installed symmetry on each side of the underwater carrier, and the sonar arrays connected with the underwater electronic section through the cable, the characterize of the system is that the said sonar arrays are consisted of a transmitting linear array which transmits linear frequency modulation signals and three and over three parallel receiving linear arrays which are arranged in same space and made of piezoelectric, wherein the transmitting linear array connects with the terminal of the power amplifier of the transmitter included in the underwater electronic section, the parallel receiving linear arrays connect with the preamplifier of the receiver included in the underwater electronic section, the space between the two adjacent parallel receiving linear arrays is d,λ > d $m(G) λ/2, wherein λ is the wavelength. It can improve greatly the precision of the bathymetric exactly under the sonar that the physiognomy of the seabed is measured by using this system. It can well detect the seabed by using the seabed automatic measuring of the invention, that is the multiple arrays beam-orientation evaluating technology, cancel the multipath signals and give the precision of the bathymetric and the isobath graphic.

An Interview with Min Zhu, Webex Founder and Active Venture Investor in China. In a public speech on April 21, 2007, Bill Gates acknowledged, “There was a survey done in the US that asked where the next Bill Gates will come from. Sixty per cent of the United States said that the next stunning success would come from Asia. I think it’s true and amazing that it’s so well organized that the investment and change here are leading to very innovative work”. To learn more about the current status of venture investment in China, we interviewed Mr. Min Zhu, who co-founded Webex in Silicon Valley, and recently moved to China to focus on venture capital investment. He answered JABS questions on May 12, 2007 in Hangzhou, China.

A magnetic head for banknote detection, comprising: a magnetoresistive sensor chip (41), and a magnetic bias unit (45) disposed on one side of the magnetoresistive sensor chip (41) away from the detection face (40) of the magnetic head for banknote detection, and separated from the magnetoresistive sensor chip (41); the magnetoresistive sensor chip (41) comprises a bridge circuit having a magneto sensitive element on a bridge arm; the sensitive direction (49) of the magneto sensitive element is parallel to the detection face (40) of the magnetic head for banknote detection; and the magnetic bias unit (45) has a recessed structure; the recessed structure is configured such that the magnetic field generated by the magnetic bias unit (45) has the small component in the direction parallel to the detection face (40), enabling the magneto sensitive element to work in a linear region. The magnetic head for banknote detection has greater sensitivity and a higher signal-to-noise ratio.

In this article, we first prove that the length increase of TiO 2 nanorods by extending reaction time is infeasible for improving dye-sensitized solar cells (DSSCs) efficiency because the longer growth time will lead to combination of nanorods from the roots part and formation of dense film. Then a TiO 2 nanorod-nanoparticle mesoporous film composite anode structure is designed and fabricated that serves as a model architecture for efficient cell devices as it simultaneously offers a large surface area, good light-scattering characteristics and a highly conductive pathway for charge carrier collection. Under standard solar cell measurement conditions, a photovoltaic conversion efficiency of 2.51% is obtained from the nanorod-nanoparticle film composite structure, which is higher than that of pure TiO 2 nanorods DSSC (1.11%). By another surface treatment process with TiCl 4, the DSSC efficiency based on such composite TiO 2 anode is further improved to 3.25%. [All rights reserved Elsevier].

In an attempt to improve implant-bone integration and accelerate bone fracture healing from resisting osteoclastic resorption point of view, we have employed a novel procedure to develop a mesoporous silica nanoparticles/hydroxyapatite (MSNs/HA) composite coating onto stainless Kirschner wire substrate. Characterizations of the surface microstructures indicated enlarged specific surface area compared to HA-coated wires as control, thus the MSNs/HA composite coated implants are endowed with abilities to locally deliver biomedical substances and enhance fracture healing. Herein, zoledronic acid (ZOL) as a model drug, different doses of which were immobilized in the mesoporous coating toward decreasing osteoclastic resorption activity. The loading capacities of ZOL increased almost eight-folds to that of pure HA coating, and the introduction of MSNs obviously retarded ZOL release to achieve a more sustained release profile. After certain periods of osteoclast like cells co-culturing with ZOL contained wires, tartrat-resistant acid phosphatases (TRAP) staining of polynucleated cells and a pit formation assay were performed to investigate the ZOL dose-dependent anti-resorption activity. The promoted local effect on osteoclasts will be of clinical benefit to support implant integration and bone repair.

Background Parkinson's disease (PD) is a common neurodegenerative disease, characterized by progressive loss of dopaminergic (DA) neurons in the substantia nigra. Recent investigations have shown that mitochondrial fragmentation, an early event during apoptosis, is implicated in the degeneration of DA neurons in PD, and more importantly, preventing mitochondrial fragmentation could rescue cell death in several PD models. Therefore, mitochondrial dynamics may be a therapeutic target for early intervention in PD. However, much remains unknown about the mechanism underlying mitochondrial fragmentation in PD. Methods The alterations in mitochondrial morphology, cell apoptosis, and mitochondrial shaping protein levels were detected after SH-SY5Y cells were treated with various doses of MPP+ or rotenone. Results Mitochondrial fragmentation is an early event during apoptosis caused by MPP+ but not rotenone, and Trichostatin A (TSA), a commonly used histone deacetylase (HDAC) inhibitor, selectively rescues mitochondrial fragmentation and cell death induced by lower doses of MPP+. Mitochondrial fragmentation triggered by lower doses of MPP+ may be a result of Mfn2 down-regulation, which could be completely reversed by TSA. Further investigation suggests that TSA prevents MPP+-induced Mfn2 down-regulation via inhibiting histone deacetylation over Mfn2 promoter and alleviating its transcriptional dysfunction. Conclusions Histone deacetylase inhibitors prevent mitochondrial fragmentation and elicit early neuroprotection in PD cell model induced by MPP+. Hence, HDAC inhibitors may be a potential early treatment for PD.

The present invention provides adipose-derived stem cells and lattices. In one aspect, the present invention provides a lipo-derived stem cell substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The cells can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both $i(in vivo) and $i(in vitro). Additionally, the cells can be expanded and cultured to produce hormones and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides a lipo-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue. The lattice can be used as a substrate to facilitate the growth and differentiation of cells, whether $i(in vivo) or $i(in vitro), into anlagen or even mature tissues or structures.

We study the photoluminescence (PL) of monocrystalline silicon irradiated by femtosecond laser pulses in different environments (deionized water and air) and energy intensities. The fluorescence spectroscopy measurement results indicate that the visible blue luminescence is observed both from the silicon surfaces ablated in the deionized water and air. The more interesting phenomenon is that the position and shape of the emission luminescence peaks in the visible range are substantially the same at the same excitation wavelength 330 nm. Compared with the granular-like microstructure generated on the silicon surface in air, the smaller and stripe-like microstructure is formed in the deionized water as the field emission scanning electron microscope (FESEM) measures. The results of the energy dispersive spectroscopy (EDS) show that silicon and oxygen is the main elemental composition on laser-induced silicon surfaces, and the oxygen content on the sample surfaces formed in air is nearly four times more than that in the deionized water. The studies confirm that oxygen element plays an important role in PL enhancement. The PL is not merely caused by the oxygen defects or quantum confinement effects, but is commonly decided by the concentration distribution of SiOx (x < 2) and the depth of the surface microstructure. The PL achieves the strongest only when the surface microstructure depth is not too deep and the shallow low oxide SiO, is intensive. (C) 2015 Elsevier B.V. All rights reserved.

A unique 3D Cu(II) complex based on a molybdate oxide cluster and 5-triazole isophthalic acid was synthesized under hydrothermal condition: {Cu-2(HL)(2)[Mo4O13]}center dot 2H(2)O (H2L = 5-triazole isophthalic acid) (1). Compound 1 shows a spin canting magnetization behavior, and a definite hysteresis loop with a large coercive field of 6.85 kOe.

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Caloric restriction (CR) has a well-known insulin sensitizing effect in vivo. Although this effect has been confirmed in rodents and primates for many years, its precise molecular mechanisms remain unknown. Here we show a significant increase in plasma adiponectin and a decrease in blood glucose, plasma triglyceride and insulin levels in rats maintained on CR diet for 2, 10, 15, and 20 months. Long-term CR rats exhibited significantly higher insulin-stimulated insulin receptor tyrosine phosphorylation and lower PTP-1B activity both in liver and skeletal muscle than those observed in rats fed ad libitum (AL). In addition, the triglyceride levels in these tissues were significantly lower in long-term CR animals. Interestingly, concentrations of plasma adiponectin in long-term CR rats were associated with increased expression of the transcription factor mRNAs for the peroxisome proliferator-activated receptor (PPAR)α, γ and δ, but decreased expression for SREBP-1c, resulting in a concerted modulation in the expression of key transcription target genes involved in fatty acid oxidation and energy combustion in liver. Taken together, our findings suggest an important role for adiponectin in the beneficial effects of long-term CR.

Provided are a CaMg2-based alloy hydride material for hydrolysis production of hydrogen, a preparation method therefor and a use thereof. The material has a general formula of CaMgxMyHz, wherein M is Ni, Co or Fe, 1.5 ¡Ü x £¼ 2.0, 0 £¼ y ¡Ü 0.5, and 3 ¡Ü z £¼6. The preparation method for the material comprises the following steps: (1) stacking three pure metal block materials in a crucible, wherein a metal block material M is placed at the top; (2) installing the crucible in a high-frequency induction melting furnace, evacuating and introducing an argon gas; (3) starting the high-frequency induction melting furnace to heat at a low power first, then increasing the power to uniformly fuse same; and thereafter cooling with the furnace to obtain an alloy ingot, and hammer-milling to obtain a hydrogen storage alloy based on CaMg2; and (4) hydrogenating the hammer-milled hydrogen storage alloy to obtain the material for hydrolysis production of hydrogen. The preparation method is simple and low in cost. The material can absorb hydrogen at normal temperature with a good hydrogen absorption performance. The prepared hydrogen is pure, and can be directly introduced into and used in a hydrogen fuel battery.