A patient monitor and a multi-MCU memory data exchange device for same comprise at least two MCUs (100), an SPI bus (200), and at least two memories (300). The MCUs (100) are connected to each other through the SPI bus (200). The MCUs (100) are each independently connected to the memories (300). The SPI bus (200) is an SPI bus (200) in DMA mode, and the memories (300) connected to the MCUs (100) exchange data with each other through the SPI bus (200) in DMA mode. The patient monitor and the multi-MCU memory data exchange apparatus of same automatically exchange data in the memories (300) respectively connected to the MCUs (100) at a fixed clock frequency. For the MCUs (100), data that needs to be exchanged only needs to be placed in the respective memories (300) at such a fixed clock frequency, so as to achieve the objective of high speed communication; in addition, as the MCUs (100) are connected through the SPI bus (200), wiring of the entire apparatus is simple. Because an SPI DMA mode is used, the intervention of an MCU is not needed, so that a system overhead is lowered and system efficiency is enhanced.
Hepatic fibrosis is a common response to liver injury that occurs in almost all liver diseases and is characterized by an excessive deposition of extracellular matrix, which can cause hepatic dysfunction and develop into cirrhosis. There is no curative treatment except liver transplantation and few treatments have been thoroughly validated in the clinic or commercialized as a therapy. Recently, sorafenib, an FDA approved molecular targeted drug for the treatment of advanced hepatocellular and renal cell carcinomas, has been reported to exert anti-fibrotic effects in liver fibrosis. Animal models showed that sorafenib ameliorated intrahepatic vascular resistance, reduced portal hypertension, and reduced intrahepatic fibrosis, inflammation and angiogenesis. In this review, we highlight the potential molecular, cellular, microenvironmental mechanisms underlying the antifibrotic effects of sorafenib in fibrotic liver disease, and briefly discuss the potential of sorafenib for hepatic fibrogenesis and major complications in clinical treatments. There is a long way to go before sorafenib can be applied in preclinical practice and clinical therapy of liver fibrosis. Further studies are required to clarify its anti-fibrotic role, effective dose, and side effects.
A display panel and a manufacturing method therefor, and a display device. The display panel comprises a first substrate (10) and a second substrate (20) arranged opposite each other, wherein a first common electrode (101) and a pixel electrode (200) arranged at different layers are arranged on the first substrate (10), and the first common electrode (101) is closer to the second substrate (20) relative to the pixel electrode (200); a second common electrode (102) is arranged on the second substrate (20), and the second common electrode (102) is electrically connected to the first common electrode (101); and an orthographic projection of the second common electrode (102) on the first substrate (10) has an overlapping area with a data line (Data) on the first substrate (10), and an orthographic projection of the first common electrode (101) on the first substrate (10) has no overlapping area with the data line (Data).
A shift register unit, a shift register circuit and a display panel. The shift register unit comprises: an input circuit (10) used for transmitting a power supply signal to a pull-up node in response to an input signal; an output circuit (20) used for transmitting a clock signal to a signal output terminal in response to a voltage signal of the pull-up node; a reset circuit (30) used for transmitting a reference signal to the pull-up node and the signal output terminal in response to a reset signal; a first pull-down control circuit (40) used for transmitting the reference signal to a pull-down control node and a pull-down node respectively in response to the voltage signal of the pull-up node; a second pull-down control circuit (50) used for transmitting the power supply signal to the pull-down control node and the pull-down node in response to the power supply signal; and a pull-down circuit (60) used for transmitting the reference signal to the pull-up node and the signal output terminal in response to the voltage signal of the pull-down node.
A display substrate and a driving method therefor, and a display panel. The display substrate comprises a base substrate (1), and gate lines (2), data lines (3) and gate driving circuits (4) which are located above the base substrate (1); the gate lines (2) are connected to the gate driving circuits (4); the base substrate (1) is further provided thereon with electrostatic rings (5) and a control component corresponding to at least one gate line (2); each gate line (2) is connected to the electrostatic rings (5) by means of corresponding control components; the electrostatic rings (5) are used for loading a control voltage at a non-working stage to start the control component; and the control component is started at the non-working stage so that the voltage on the gate line (2) is a start voltage.
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