Creat membership Creat membership
Sign in

Forgot password?

Confirm
  • Forgot password?
    Sign Up
  • Confirm
    Sign In
home > search

Now showing items 97 - 112 of 3547

  • Speakers and Sleepers: Chang-Rae Lee\"s \"Native Speaker,\" Whitman, and the Performance of Americanness

    Christian Moraru  

    Focusing on Chang-rae Lee 1995 “post-ethnic” classic Native Speaker, this article dwells on the novel’s “legend” theme to suggest that Lee’s book itself is a legend twice: first, because it furnishes the “legible” appearance, the story in which Lee comes before his readers, and second, because this story itself appears, is seen, and lends itself to reading (is made legible) via a legend in the etymological sense of the word. Embedded in the novel, this “key” warrants a certain reading of the book. Further, Moraru offers that the key is fundamentally Whitmanesque and by the same token central to Lee’s engagement with America’s tradition and culture. According to the critic, Whitman, the “legendary” native precursor, helps Lee lay his own claim to American writer status; Korean-born Lee becomes a “natural,” naturalizes himself into America and its letters via the emblematically American, Whitman intertext lodged inside his novel.
    Download Collect
  • Generation of functional eggs and sperm from cryopreserved whole testes

    Lee, S.   Iwasaki, Y.   Shikina, S.   Yoshizaki, G.  

    Download Collect
  • Maternal Inflammation at Delivery Affects Assessment of Maternal Iron Status

    Lee, S.   Guillet, R.   Cooper, E. M.   Westerman, M.   Orlando, M.   Pressman, E.   O\"Brien, K. O.  

    Pregnant adolescents (aged <= 8 y, n = 253) were followed from >= 12 wk of gestation to delivery to assess longitudinal changes in anemia and iron status and to explore associations between iron status indicators, hepcidin, and inflammatory markers. Hemoglobin, soluble transferrin receptor (sTfR), ferritin, serum iron, erythropoietin (EPO), hepcidin, C-reactive protein, interleukin-6 (IL-6), folate, and vitamin B-12 were measured, and total body iron (TB I) (milligrams per kilogram) was calculated using sTfR and ferritin values. Anemia prevalence increased from trimesters 1 and 2 (3-5%, <28 wk) to trimester 3(25%, 33.2 +/- 3.7 wk, P<0.0001). The prevalence of iron deficiency (sTfR >8.5 mg/L) doubled from pregnancy to delivery (7% to 14%, P = 0.04). Ferritin and hepcidin concentrations at delivery may have been elevated as a consequence of inflammation because IL-6 concentrations at delivery were 1.6-fold higher than those obtained at 26.1 +/- 3.3 wk of gestation (P < 0.0001), and a positive association was found between IL-6 and both hepcidin and ferritin at delivery (P < 0.011. EPO was consistently correlated with hemoglobin (r= -0.36 and 0 43, P < 0.001), ferritin (r = -0.37 and -0.32, P < 0.0001), sTfR (r = 0.35 and 0.25, P < 0.001), TBI (r = -0.44 and -0.37, P < 0.0001), and serum iron (r= -0.22 and -0.16, P < 0.05) at mid-gestation and at delivery, respectively. EPO alone explained the largest proportion of variance in hemoglobin at 26.0 +/- 3.3 wk of gestation (R-2 = 0.13, P = 0.0001, n = 113) and at delivery (R-2 = 0.19, P < 0.0001, n = 192). Pregnant adolescents are at high risk of anemia. EPO is a sensitive indicator of iron status across gestation, is not affected by systemic inflammation, and may better predict risk of anemia at term. The trial was registered at clinicaltrials.gov as NCT01019902.
    Download Collect
  • Oscillon in Einstein-scalar system with double well potential and its properties.

    Ikeda, Taishi   Yoo, Chul-Moon   Cardoso, Vitor   Gwak, B.   Kang, G.   Kim, C.   Kim, H.-C.   Lee, C.-H.   Lee, J.   Lee, S.   Lee, W.  

    Download Collect
  • Sparse estimation of gene-gene interactions in prediction models

    Lee, S.   Pawitan, Y.   Ingelsson, E.   Lee, Y.  

    Download Collect
  • Increased risk for atypical fractures associated with bisphosphonate use

    Lee, S.   Yin, R. V.   Hirpara, H.   Lee, N. C.   Lee, A.   Llanos, S.   Phung, O. J.  

    Download Collect
  • Increased Leptin and Leptin Receptor Expression in Dogs With Gallbladder Mucocele

    Lee, S.   Kweon, O.-K.   Kim, W.H.  

    Download Collect
  • Heart failure in Asia: the present reality and future challenges

    Lee, S.   Khurana, R.   Leong, K. T. G.  

    Heart failure (HF) is the final pathway of multiple cardiac diseases. It exerts its clinical burden globally. In this brief review, its epidemiology in Asia is described, followed by an overview of the evolution of past therapies to present strategies available in Asia, and finally, future challenges are identified.
    Download Collect
  • Impact of Ramped Vanes on Normal Shock Boundary Layer Interaction

    Lee, S.   Loth, E.  

    Large-eddy simulations of a vortex generator embedded upstream of a normal shock boundary-layer interaction followed by a subsonic diffuser were conducted. In particular, the "ramped-vane" flow control device was placed in a supersonic boundary layer with a freestream Mach number of 1.3 and a Reynolds number of 2400 based on momentum thickness. The ramped vane had a height of 0.52 delta and generated strong streamwise vorticity that entrained the high-momentum flow to the near-wall region. This contributed to decreasing the shock-induced flow separation while significantly increasing the skin friction coefficient in the diffuser where a strong adverse pressure gradient was present. In addition, it was found that the high-momentum flow persisted far downstream of the shock interaction region, which yielded reductions of both the displacement thickness and the shape factors compared to the uncontrolled case.
    Download Collect
  • Comprehension of a simplified assent form in a vaccine trial for adolescents

    Lee, S.   Kapogiannis, B. G.   Flynn, P. M.   Rudy, B. J.   Bethel, J.   Ahmad, S.   Tucker, D.   Abdalian, S. E.   Hoffman, D.   Wilson, C. M.   Cunningham, C. K.  

    Download Collect
  • Optimal tests for rare variant effects in sequencing association studies

    Lee, S.   Wu, M. C.   Lin, X.  

    With development of massively parallel sequencing technologies, there is a substantial need for developing powerful rare variant association tests. Common approaches include burden and non-burden tests. Burden tests assume all rare variants in the target region have effects on the phenotype in the same direction and of similar magnitude. The recently proposed sequence kernel association test (SKAT) (Wu, M. C., and others, 2011. Rare-variant association testing for sequencing data with the SKAT. The American Journal of Human Genetics 89, 82-93], an extension of the C-alpha test (Neale, B. M., and others, 2011. Testing for an unusual distribution of rare variants. PLoS Genetics 7, 161-165], provides a robust test that is particularly powerful in the presence of protective and deleterious variants and null variants, but is less powerful than burden tests when a large number of variants in a region are causal and in the same direction. As the underlying biological mechanisms are unknown in practice and vary from one gene to another across the genome, it is of substantial practical interest to develop a test that is optimal for both scenarios. In this paper, we propose a class of tests that include burden tests and SKAT as special cases, and derive an optimal test within this class that maximizes power. We show that this optimal test outperforms burden tests and SKAT in a wide range of scenarios. The results are illustrated using simulation studies and triglyceride data from the Dallas Heart Study. In addition, we have derived sample size/power calculation formula for SKAT with a new family of kernels to facilitate designing new sequence association studies.
    Download Collect
  • Parental Vaccine Acceptance: A Logistic Regression Model Using Previsit Decisions

    Lee, S.   Riley-Behringer, M.   Rose, J. C.   Meropol, S. B.   Lazebnik, R.  

    Download Collect
  • Effects of Low Dose Radiation on DNA Methylation in Nuclear Power Plant Workers.

    Lee, Y.   Kim, Y. J.   Choi, Y. J.   Lee, J. W.   Lee, S.   Chung, H. W.  

    Download Collect
  • Oceanic barriers promote language diversification in the Japanese Islands

    Lee, S.   Hasegawa, T.  

    Good barriers make good languages. Scholars have long speculated that geographical barriers impede linguistic contact between speech communities and promote language diversification in a manner similar to the process of allopatric speciation. This hypothesis, however, has seldom been tested systematically and quantitatively. Here, we adopt methods from evolutionary biology and attempt to quantify the influence of oceanic barriers on the degree of lexical diversity in the Japanese Islands. Measuring the degree of beta diversity from basic vocabularies, we find that geographical proximity and, more importantly, isolation by surrounding ocean, independently explains a significant proportion of lexical variation across Japonic languages. Further analyses indicate that our results are neither a by-product of using a distance matrix derived from a Bayesian language phylogeny nor an epiphenomenon of accelerated evolutionary rates in languages spoken by small communities. Moreover, we find that the effect of oceanic barriers is reproducible with the Ainu languages, indicating that our analytic approach as well as the results can be generalized beyond Japonic language family. The findings we report here are the first quantitative evidence that physical barriers formed by ocean can influence language diversification and points to an intriguing common mechanism between linguistic and biological evolution.
    Download Collect
  • New approach to monitor transboundary particulate pollution over Northeast Asia

    Park, M. E.   Song, C. H.   Park, R. S.   Lee, J.   Kim, J.   Lee, S.   Woo, J. -H.   Carmichael, G. R.   Eck, T. F.   Holben, B. N.   Lee, S. -S.   Song, C. K.   Hong, Y. D.  

    A new approach to more accurately monitor and evaluate transboundary particulate matter (PM) pollution is introduced based on aerosol optical products from Korea's Geostationary Ocean Color Imager (GOCI). The area studied is Northeast Asia (including eastern parts of China, the Korean peninsula and Japan), where GOCI has been monitoring since June 2010. The hourly multi-spectral aerosol optical data that were retrieved from GOCI sensor onboard geostationary satellite COMS (Communication, Ocean, and Meteorology Satellite) through the Yonsei aerosol retrieval algorithm were first presented and used in this study. The GOCI-retrieved aerosol optical data are integrated with estimated aerosol distributions from US EPA Models-3/CMAQ (Community Multi-scale Air Quality) v4.5.1 model simulations via data assimilation technique, thereby making the aerosol data spatially continuous and available even for cloud contamination cells. The assimilated aerosol optical data are utilized to provide quantitative estimates of transboundary PM pollution from China to the Korean peninsula and Japan. For the period of 1 April to 31 May, 2011 this analysis yields estimates that AOD as a proxy for PM2.5 or PM10 during long-range transport events increased by 117-265% compared to background average AOD (aerosol optical depth) at the four AERONET sites in Korea, and average AOD increases of 121% were found when averaged over the entire Korean peninsula. This paper demonstrates that the use of multi-spectral AOD retrievals from geostationary satellites can improve estimates of transboundary PM pollution. Such data will become more widely available later this decade when new sensors such as the GEMS (Geostationary Environment Monitoring Spectrometer) and GOCI-2 are scheduled to be launched.
    Download Collect
  • Development of force measurement system of bobsled for practice of push-off phase

    Lee, S.   Kim, T.   Lee, S.   Kil, S.   Hong, S.  

    A force measurement system for the push bar and handle of a bobsled was developed to analyse the forces exerted by members of a two-person bobsled crew. The developed system comprised eight load cells, an encoder, four cameras, and a data acquisition device and was installed on a test sled. Two load cells were installed in each of the brakeman’s push handle and the driver’s side push bar, and two load cells were located on each of the right and left ends of the push bar. The operator could adjust the sampling rate of each load cell from 50 to 200 samples/s. The motion of the crew member was recorded with the four cameras. The sled speed was recorded along with the force data. For convenient monitoring and analysis of the measured data, the four camera images were merged into a single video image, and the force data were plotted on this merged image. This image contained all of the measured data and was transmitted wirelessly to a monitor at a remote site in real time. The data measurement software was developed using LabVIEW, and the force and speed of the sled were recorded as a technical data management streaming file. The images were recorded as Audio Video Interleaved files. The technical data management streaming file was automatically converted into an Excel file when the measurement stopped. The vector components of the forces exerted by crew members were measured using this system. The data were used to analyse the exerted force with the aim of increasing the starting speed of the Korean bobsled crew.
    Download Collect
2 3 4 5 6 7 8 9 10 11

Contact

If you have any feedback, Please follow the official account to submit feedback.

Turn on your phone and scan

Submit Feedback