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Now showing items 1 - 16 of 139

  • ION EXCHANGE MEMBRANE AND MANUFACTURING METHOD THEREFOR

    The present invention relates to an ion exchange membrane and a manufacturing method therefor and, more specifically, to an ion exchange membrane comprising a cross-linked sulfonated triblock copolymer and carbon nanotube, which is utilizable in a redox flow energy storage device, etc. due to high ion conductivity, mechanical strength and ion selectivity. The ion exchange membrane of the present invention has superior ion selectivity and mechanical strength and thus can greatly improve the performance of a fuel battery, etc. when applied thereto.
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  • Morphology and Conductivity in Ionic Liquid Incorporated Sulfonated Block Copolymers

    Kim, Sung Yeon   Yoon, Eunjin   Joo, Taiha   Park, Moon Jeong  

    We have explored the link between morphologies and conductivities for ionic liquids (ILs) incorporated block copolymer electrolytes by combining small-angle X-ray scattering, transmission electron microscopy, and impedance spectroscopy. The block copolymer electrolytes investigated in present study are a series of partially sulfonated poly(styrenesulfonate-b-methylbutylene) (S(n)MB(m)) copolymers with different molecular weights and sulfonation levels (SLs). Imidazolium-based Its are selectively doped into hydrophilic domains of S(n)MB(m) copolymers, and various morphologies have been observed as a function of the amount of absorbed ILs and SLs in S(n)MB(m) copolymers. We have demonstrated that the morphologies of ILs impregnated S(n)MB(m) copolymers are sensitive function of kinds of counteranions in IL, yielding remarkable discrepancy in conductivities. When the morphology of sample is appeared to be a lamellar structure, significant reduction in through-plane conductivity value was detected due to the nonrandom orientation of microdomains. In contrast, hexagonally perforated lamellar forming samples exhibit the highest conductivities in both through-plane and in-plane directions on account of the better connectivity of ionic domains along the perforated hydrophilic phases. Once the morphology effects were vanished by employing highly sulfonated S(n)MB(m) copolymers, it has been revealed that the conductivities of Its incorporated copolymers are closely related to the polarity of ILs as confirmed by solvation dynamics study.
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  • Confinement Effects on Watery Domains in Hydrated Block Copolymer Electrolyte Membranes

    Kim, Sung Yeon   Park, Moon Jeong   Balsara, Nitash P.   Jackson, Andrew  

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  • Antiestrogens and the Formation of DNA Damage in Rats:? A Comparison

    Kim, Sung Yeon   Suzuki, Naomi   Laxmi, Y. R. Santosh   Umemoto, Atsushi   Matsuda, Tomonari   Shibutani, Shinya  

    Tamoxifen (TAM) has been used as an agent for the treatment and prevention of breast cancer. However, long-term treatment of TAM in women increases the risk of developing endometrial cancer. The secondary cancer may be due to the genotoxicity of TAM. To find safer alternatives, four selective estrogen receptor modulators (SERMs), 4-hydroxytamoxifen (4-OHTAM), toremifene (TOR), raloxifene (RAL), and ICI 182,780, were administered to rats with an equimolar dose of TAM [54 mu mol/kg (20 mg/kg)/day, p.o. for 7 days]. To evaluate the genotoxicity of each SERM, the presence of bulky DNA adducts was determined by P-32-postlabeling/polyacrylamide gel electrophoresis and P-32-postlabeling/high-performance liquid chromatography. The formation of 7,8-dihydro-8-oxodeoxyguanosine (8-oxodG) was analyzed as a marker of typical oxidative damage, using liquid chromatography electrospray tandem mass spectrometry. Among the SERMs, bulky DNA adducts were detected in the livers of rats treated with TAM; the total amount of TAM-DNA adducts was 26.1 adducts/10(7) nucleotides. However, with a detection limit of similar to 2 adducts/10(9) nucleotides, no bulky DNA adducts were observed with 4-OHTAM, TOR, RAL, or ICI 182,780. In addition, no significant increase of hepatic 8-oxodG lesions was detected in rats treated with any of the antiestrogens. Therefore, TOR, RAL, and ICI 182,780 are likely to be less genotoxic than TAM.
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  • Proton Hopping and Diffusion Behavior of Sulfonated Block Copolymers Containing Ionic Liquids

    Kim, Sung Yeon   Lee, Joungphil   Park, Moon Jeong  

    We have investigated the dependence of proton hopping and diffusion behavior of nanostructured poly(styrenesulfonate-b-methylbutylene) (PSS-b-PMB) block copolymers containing imidazolium-based ionic liquids (ILs) on the type and the composition of ILs. Pulsed-field gradient spin-echo nuclear magnetic resonance experiments suggest that fast proton hopping is facilitated by higher imidazolium contents in the ILs. On the contrary, the alkyl substituent at the protic position of imidazole results in a 2-fold reduction in the self-diffusion coefficient for proton hopping, becoming comparable to vehicle diffusion in the temperature window examined. The anion of ILs makes a significant impact on the activation barrier for proton conduction, leading to conductivities differing by a few orders of magnitude, depending on the type of anion in the ILs. Notably, a high proton transference number of 0.81 was achieved for the IL-containing PSS-b-PMB copolymers (compared to the low value of 0.52 for neat ILs) by optimizing the composition and the type of ILs. This increase is attributed to specific interactions between the ILs and the polymer matrix, affecting the nature of hydrogen bonds and ionic aggregate structures. This study provides valuable insights into the factors affecting the proton transport efficiency of IL-containing polymers, enabling the design of new polymer electrolytes characterized by both fast proton conduction and high proton transference numbers.
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  • The Clinical Characteristics of Macroprolactinemia

    Choi, Young Ju   Kang, Jun Goo   Kim, Sung Yeon   Hong, Eui Sil   Kim, Sang Wan   Shin, Chan Soo   Kim, Seong Yeon   Cho, Bo Youn   Lee, Hong Kyu  

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  • Genotoxic Mechanism of Tamoxifen in Developing Endometrial Cancer

    Kim, Sung Yeon   Suzuki, Naomi   Santosh Laxmi, Y. R.   Shibutani, Shinya  

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  • MG-TI-AL COMPOSITE METAL HYDROXIDE HAVING A LAMINATED STRUCTURE, AND A PRODUCTION METHOD THEREFOR

    The present invention relates to a novel Mg-Ti-Al composite metal hydroxide of chemical formula 1 below and to a production method therefor. Mg-Ti-Al composite metal hydroxide particles can be obtained by subjecting a solution containing a magnesium salt and a titanium salt to ultrasound processing and carrying out a high-temperature and high-pressure reaction with a solution containing an aluminium salt, in the proportions of the metal elements comprised in the Mg-Ti-Al composite metal hydroxide of chemical formula 1 below, thereby giving the advantageous effects that the halogen capturing ability is excellent and, when used in a polymer, degradation and early-staining prevention properties and transparency are outstanding. In the above formula, A1 n- and A2 m- are respectively anions having valences of n and m, a/c is from 1 to 5, and b, c, d and x are numbers satisfying the conditions 0 (adsbygoogle = window.adsbygoogle || []).push({}); SONG, Seok Keun (501-401, Yangji Maeul 5-danji Apt. 676, Janghang 2-dong, Ilsandong-gu, Goyang-si, Gyeonggi-do 410-739, 410-739, KR) 송석근 (경기도 고양시 일산동구 장항2동 676번지 양지마을 5단지 아파트 510-401, 410-739 Gyeonggi-do, 410-739, KR) KIM, Sung Yeon (406-701, Poongrim I-won 4-cha Apt. Wolgot-dong, Siheung-si, Gyeonggi-do 429-928, 429-928, KR) 김성연 (경기도 시흥시 월곶동 풍림아이원4차 406-701, 429-928 Gyeonggi-do, 429-928, KR) KR2010/002218 10/13/2011 04/09/2010 Click for automatic bibliography generation SHIN WON CHEMICAL CO., LTD. (106 1 Ra, Sihwa Industrial Complex 1236-5, Jeongwang-dong, Siheung-si, Gyeonggi-do 429-914, 429-914, KR) 신원화학 주식회사 (경기도 시흥시 정왕동 1236-5 시화공단 1라 106호, 429-914 Gyeonggi-do, 429-914, KR) SHIN WON INDUSTRIAL CO., LTD. (1203-4, Wonjeong-ri Poseung-eup, Pyeongtaek-si, Gyeonggi-do 451-764, 451-764, KR) 신원산업 주식회사 (경기도 평택시 포승읍 원정리 1203-4, 451-764 Gyeonggi-do, 451-764, KR) SONG, Seok Keun (501-401, Yangji Maeul 5-danji Apt. 676, Janghang 2-dong, Ilsandong-gu, Goyang-si, Gyeonggi-do 410-739, 410-739, KR) 송석근 (경기도 고양시 일산동구 장항2동 676번지 양지마을 5단지 아파트 510-401, 410-739 Gyeonggi-do, 410-739, KR) C01F7/00 ; C01B13/36 ; C01F5/00 ; C01G23/00 ; C08K3/22 Download PDF WO/2011/126168A1 PDF help EP0749941 1996-12-27 JP2001002408A 2001-01-09 KR20090037861A 2009-04-16 JP2008214480A 2008-09-18 3879523 1975-04-22 4458026 1984-07-03 4904457 1990-02-27 KR20010108920A 2001-12-08 KR20000049194A 2000-07-25 See also references of EP 2557066A4 MICROPOROUS AND MESOPOROUS MATERIALS, vol. 111, 2008, pages 12 - 17 CHO, In-je (Newkorea International Patent & Law Office, No.301 3rd Fl., Buok Bldg,,#648-18, Yeoksam-dong, Gangnam-gu, Seoul 135-911, 135-911, KR)
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  • Formation of Tamoxifen?DNA Adducts in Human Endometrial Explants Exposed to α-Hydroxytamoxifen

    Kim, Sung Yeon   Suzuki, Naomi   Laxmi, Y. R. Santosh   McGarrigle, Barbara P.   Olson, James R.   Sharma, Moheswar   Sharma, Minoti   Shibutani, Shinya  

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  • α-Hydroxylation of Tamoxifen and Toremifene by Human and Rat Cytochrome P450 3A Subfamily Enzymes

    Kim, Sung Yeon   Suzuki, Naomi   Santosh Laxmi, Y. R.   Rieger, Robert   Shibutani, Shinya  

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  • A COMPOSITION COMPRISING AN EXTRACT OF PUERARIAE RADIX SHOWING IMMUNE ENHANCING ACTIVITY AND THE USE THEREBY

    The inventive composition of the present invention has increasing effect on the release of immune-modulating factors such as NO and TNF-α; the stimulating effect on spleen cell proliferation; increasing effect on the production of cytokines such as IFN-γ and TNF-αand TLR-4 activation in immune cell as well as immune-modulating effect on rotavirus-induced enteritis, rotavirus-specific immune response, rotavirus-infected polyclonal antibody stimulation and immune receptor expression using by C57BL/6 newborn mice together with the preventive test on bacterial infection symptom effect using by ICR mice, therefore, it can be useful as a medicament, health functional food and feed composition for treating, preventing and alleviating immunodeficiency disease in human and animal.
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  • Enhanced proton transport in nanostructured polymer electrolyte/ionic liquid membranes under water-free conditions

    Kim, Sung Yeon   Kim, Suhan   Park, Moon Jeong  

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  • PRESSURE SENSITIVE DESTRUCTIBLE MICROCAPSULE CONTAINING SCRUBBING AGENTS, PREPARATION METHOD THEREFOR, AND USE THEREFOR

    According to the present invention, provided is a core-shell structured pressure sensitive destructible microcapsule containing scrubbing agents, comprising: a scrub core (A) comprising disintegrable or non-disintegrable scrubbing particles or granules; and a pressure sensitive destructible wall layer (B) encompassing the same, wherein the pressure sensitive destructible wall layer (B) comprises a wall-forming material, a binder and optional solid fine particles. The microcapsule containing the scrub core (A) according to the present invention has high storage durability, maintenance durability and aesthetic value, can prevent the swelling, dissolution and disintegration of scrubbing agents caused by a carrier, and can be easily destroyed by pushing, rubbing, polishing or scrubbing with the hands or a tool (cotton fabric, sponge or paper) so as to readily and rapidly supply fresh scrubbing particles with no swelling, dissolution and disintegration into a carrier, thereby improving scrubbing effects, that is, exfoliation effects.
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  • The Effects on Visceral Fat and Cardiovascular Risk Factors of Testosterone Replacement in Secondary Hypogonadal Men

    Hong, Eui Sil   Kim, Sung Yeon   Choi, Young Ju   Kim, Sang Wan   Shin, Chan Soo   Park, Kyong Soo   Jang, Hak Chul   Kim, Seong Yeon   Cho, Bo Youn   Lee, Hong Kyu  

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  • COMPOSITION FOR AMELIORATING MENOPAUSAL SYMPTOMS CONTAINING ANGELICA GIGAS, CNIDIUM OFFICINALE AND CINNAMOMUM CASSIA AS ACTIVE INGREDIENTS

    The present invention relates to a composition for ameliorating menopausal symptoms containing Angelica gigas, Cnidium officinale and Cinnamomum cassia as active ingredients. The present invention relates to a composition containing, as an active ingredient, an extract from a mixture of Angelica gigas, Cnidium officinale and Cinnamomum cassia which are mixed at a weight ratio of 1.5 to 2.5:1:1, and is capable of ameliorating menopausal symptoms by being administered at a dose of 50 to 200 mg/kg/day (on the basis of oral administration to a 5-week-old mouse).
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  • First person – Sung Tae Kim

    Kim, Sung Tae  

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