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Severe vitamin D deficiency in a patient with sickle cell disease: a case study with literature review.

Journal:
Journal of pediatric hematology/oncology


Issue Date:
2014


Abstract(summary):

PURPOSE: Vitamin D is essential for the normal absorption of calcium and to maintain calcium homeostasis. Vitamin D deficiency results in rickets, osteomalacia, and bony changes in the spine. Sickle cell disease patients are at an increased risk of vitamin D deficiency.; CASE PRESENTATION: We describe a case of severe vitamin D deficiency and response to vitamin D supplementation in a patient with sickle cell disease.; CONCLUSIONS: Currently, there are no recommendations for calcium and vitamin D supplementation in sickle cell patients. Vitamin D deficiency in these patients may be due to poor absorption.=20


Page:
293---296


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