Optimal Formulation of palmitoyl-KTTKS for Transdermal Delivery
Journal:
YAKHAK HOEJI=09
Issue Date:
2017
Abstract(summary):
Palmitoyl KTTKS (Pal-KTTKS), a derivative of KTTKS has been known for better skin penetration to stimulateskin matrix replenishment through topical application. The main purpose of this study was to find the opitmal formulationof pal-KTTKS for transdermal delivery. In this study, three kind of formulaion - hydrophilic, hydrophobic andemulsion formualtion were examined. On in vitro retention study, pal-KTTKS was retained with higher amount in stratumcorneum than viable layer. The higher retention rate of pal-KTTKS was observed in the emulsion formulation than others.=09
Page:
96=09---99=09
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