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Efficient method for the synthesis of fused benzimidazole–imidazoles via deprotection and cyclization reactions

Author:
Zhong-Zhu Chen  Shi-Qiang Li  Wen-Li Liao  Zhi-Gang Xie  Ming-Shu Wang  Yun Cao  Jin Zhang  Zhi-Gang Xu  


Journal:
Tetrahedron


Issue Date:
2015


Abstract(summary):

Abstract A fused benzimidazole–imidazole scaffold was designed and synthesized using a facile procedure involving deprotection and cyclization reactions. The acidic conditions and high yields for the benzimidazole ring closure allow potential application of this efficient methodology for the design and synthesis of a range of bioactive compounds. Graphical abstract


Page:
8424-8424


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