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Mid-infrared reflectivity of experimental atheromas

Author:
Holman, Hoi-Ying N.   Bjornstad, Kathy A.   Martin, Michael C.   Mckinney, Wayne R.   Blakely, Eleanor A.   Blankenberg, Francis G.  


Journal:
Journal of Biomedical Optics


Issue Date:
2008


Abstract(summary):

We report that the pathologic components present within the atheromatous plaques of ApoE knockout mice can reflect significant amounts of mid-infrared (mid-IR) light. Furthermore, the reflected light spectra contained the unique signatures of a variety of biologic features including those found in unstable or "vulnerable" plaque. This discovery may represent a unique opportunity to develop a new intravascular diagnostic modality that can detect and characterize sites of atherosclerosis. (c) 2008 Society of Photo-Optical Instrumentation Engineers.


Page:
030503


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