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This work was to improve the bioactivity of biomedical titanium (Ti) through constructing a bioactive surface with micro/nano-topography on Ti. Firstly, Ti plates were sandblasted, acid etched and anodized (SBAO) to obtain the controlled micro/nano-topography. And then, heat treatment was used to change the amorphous phase of Ti oxide nanotubes to anatase on the SBAO sample. The SBAO sample and heat treated SBAO sample (SBAOT) both have super hydrophilicity mainly due to their micro/nano-topography. At last, nano-brushite was deposited on the SBAOT surface by hydrothermal treatment to further improve its bioactivity. The simulated body fluid incubation indicated that this novel coating with nano-brushite has more excellent bioactivity as compared to Ti, and SBAO and SBAOT.
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