Creat membership Creat membership
Sign in

Forgot password?

Confirm
  • Forgot password?
    Sign Up
  • Confirm
    Sign In
Creat membership Creat membership
Sign in

Forgot password?

Confirm
  • Forgot password?
    Sign Up
  • Confirm
    Sign In
Collection
For ¥0.57 per day, unlimited downloads CREATE MEMBERSHIP Download

toTop

If you have any feedback, Please follow the official account to submit feedback.

Turn on your phone and scan

home > search >

The effect of strontium-substituted hydroxyapatite coating on implant fixation in ovariectomized rats

Author:
Yunfeng Li   Qing Li   Songsong Zhu   En Luo   Jihua Li   Ge Feng   Yunmao Liao   Jing Hu  


Journal:
Biomaterials


Issue Date:
2010


Abstract(summary):

This study was designed to investigate the effects of strontium-substituted hydroxyapatite coatings with 10 mol%Ca2+ replaced by Sr2+ (10%SrHA) on implant fixation in ovariectomized (OVX) rats. Coatings of HA and 10%SrHA were prepared on the surface of titanium implant using sol-gel dip methods, and then characterized by Scanning Electron Microscope, Atomic Force Microscope, X-ray diffraction, X-ray Photoemission Spectroscopy, and an automatic scratch tester. Twelve weeks after bilateral ovariectomy, twenty OVX rats accepted implant insertion in the proximal tibiae, half with HA-coated implants and the other half with 10%SrHA coated implants. After 12-week healing period, 10%SrHA coated implants revealed improved osseointegration compared to HA, with the bone area ratio and bone-to-implant contact increased by 70.9%and 49.9%in histomorphometry, the bone volume ratio and percent osseointegration by 73.7%and 45.2%in micro-CT evaluation, and the maximal push-out force and ultimate shear strength by 107.2%and 132.9%in push out test. These results demonstrated that 10%SrHA coatings could enhance implant osseointegration in OVX rats, and suggested the feasibility of using SrHA coatings to improve implant fixation in osteoporotic bone.


Page:
9006-9014


VIEW PDF

The preview is over

If you wish to continue, please create your membership or download this.

Create Membership

Similar Literature

Submit Feedback

This function is a member function, members do not limit the number of downloads