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A concise synthesis of asymmetrical N,N '-disubstituted guanidines

Author:
O'Donovan, Daniel H.  Rozas, Isabel  


Journal:
TETRAHEDRON LETTERS


Issue Date:
2011


Abstract(summary):

We present a new and concise method for the preparation of asymmetrical N,N'-disubstituted guanidines starting from thiourea via the reaction of N-Boc-protected N'-alkyl/aryl substituted thioureas with an amine in the presence of mercury(II) chloride and triethylamine. (C) 2011 Elsevier Ltd. All rights reserved.


Page:
4117---4119


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