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Now showing items 1 - 16 of 402

  • Aging Behavior and Precipitation Analysis of Cu-Ni-Co-Si Alloy

    Xiao, Xiangpeng   Huang, Jian   Chen, Jinshui   Xu, Hai   Li, Zhao   Zhang, Jianbo  

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  • Lung Cancer in Patients With Tuberculous Fibrothorax and Empyema

    Xu, Hai   Koo, Hyun Jung   Lee, Han Na   Lim, Soyeoun   Lee, Jae Wook   Choi, Chang-Min   Kim, Mi Young  

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  • Assessment of immunotoxicity of dibutyl phthalate using live zebrafish embryos

    Xu, Hai   Dong, Xing   Zhang, Zhen   Yang, Ming   Wu, Xiangyang   Liu, Hongcui   Lao, Qiaocong   Li, Chunqi  

    Highlights • DBP inhibits neutrophils formation in transgenic zebrafish embryos. • DBP inhibits macrophage formation and phagocytosis in zebrafish embryos. • DBP up-regulates the transcript levels of T cell-related gene. Abstract This study set out to understand the immune-toxic effects of dibutyl phthalate (DBP) using transgenic, albino or AB line zebrafish. Zebrafish embryos were exposed to different concentrations of DBP, and the immune cells formation, phagocytosis ability were measured after a short-term exposure to DBP for 6 h post-fertilization (hpf) to 72 or 96 hpf. Exposure to DBP was found to inhibit the neutrophils and macrophage formation in a concentration-dependent manner. The ability of macrophage phagocytosis was all decreased after exposure to DBP, indicating the occurrence of immunotoxicity. The respiratory burst was induced, and the transcription levels of T/B cell-related genes rag1/2 were up-regulated. The overall results indicate that DBP in aquatic environment greatly influence the immune system in fish, and zebrafish embryos can serve as a reliable model for the developmental immunotoxicity of toxic-chemicals.
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  • Engineering T7 bacteriophage as a potential DNA vaccine targeting delivery vector

    Xu, Hai   Bao, Xi   Wang, Yiwei   Xu, Yue   Deng, Bihua   Lu, Yu   Hou, Jibo  

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  • Holocene peatland development along the eastern margin of the Tibetan Plateau

    Xu, Hai   Liu, Bin   Lan, Jianghu   Sheng, Enguo   Che, Shuai   Xu, Sheng  

    Knowledge of peatland initiation, accumulation, and decline or cessation is critical in understanding peatland development and the related carbon source/sink effect. In this study, we investigated the development of three peat profiles along the eastern margin of the Tibetan Plateau (ETP) and compared the results with those of our previous work along this transect. Our work showed that the initiation over the northern ETP is later and the slowdown/cessation earlier than in the middle to southern ETP. The timing of optimum peatland formation over the northern ETP lags the Holocene climatic optimum. These spatio-temporal differences are likely to be related to the intensity of Asian summer monsoon. Our work suggests that some peatlands along the ETP transect have returned or are now returning their previously captured carbon to the atmosphere and thus act as carbon sources. Some peatlands still have net accumulation at present, but the rates have been reduced concomitant with the decreasing summer monsoon intensity. We speculate that more of the previously stored carbon in the ETP peatlands will be re-emitted to the atmosphere if the aridity continues, as might occur under a continuous global-warming scenario. [All rights reserved Elsevier].
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  • Tropical/Subtropical Peatland Development and Global CH4 during the Last Glaciation

    Xu, Hai   Lan, Jianghu   Sheng, Enguo   Liu, Yong   Liu, Bin   Yu, Keke   Ye, Yuanda   Cheng, Peng   Qiang, Xiaoke   Lu, Fengyan   Wang, Xulong  

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  • Design of Compliant Mechanism Based on the Parallel Mechanism Decoupling Criterion

    Xu, Hai   Hang, Lu Bin   Cai, Jin   Fu, Zhi Yu   Zhang, Peng Ju   Cheng, Wu Shan  

    Traditionally compliant mechanism is difficult to achieve decoupling features, because of lack of definite theory and its deformability character. Whereas its counterpart - many rigid mechanisms with decoupling property have been designed and the method of mechanism design with decoupling feature is constructed. In this paper, an effective method to build equivalent transformation between rigid decoupling mechanism and compliant mechanism with decoupling property is proposed, and also applied to design new a decoupling rigid mechanism with 3-DOF. Finally, the decoupling features of the micro motion platform was verified through FEM analysis software ANSYS because of difficulty of compliant mechanism analysis.
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  • Hydroclimatic contrasts over Asian monsoon areas and linkages to tropical Pacific SSTs

    Xu, Hai   Lan, Jianghu   Sheng, Enguo   Liu, Bin   Yu, Keke   Ye, Yuanda   Shi, Zhengguo   Cheng, Peng   Wang, Xulong   Zhou, Xinying   Yeager, Kevin M.  

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  • Oscillating edge states in one-dimensional MoS2 nanowires

    Xu, Hai   Liu, Shuanglong   Ding, Zijing   Tan, Sherman J. R.   Yam, Kah Meng   Bao, Yang   Nai, Chang Tai   Ng, Man-Fai   Lu, Jiong   Zhang, Chun   Loh, Kian Ping  

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  • Coarsening behavior of (Ni, Co)2Si particles in Cu–Ni–Co–Si alloy during aging treatment

    Xiao, Xiang-Peng   Xu, Hai   Chen, Jin-Shui   Wang, Jun-Feng   Lu, Jiao   Zhang, Jiao-Bo   Peng, Li-Jun  

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    Seismic data acquired by independent simultaneous sweeping (ISS ) techniques are processed is to attenuate random uncompressed cross-talk signals and improve the resolution of the pre-stack migrated time image. A frequency- varying mean filter is applied on cross- spread offset-azimuth gathers of the data. The frequency-space domain filter may vary its window size according to the characteristics of the cross-talk.
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  • Effects of Bearing Preload, Oil Volume, and Operating Temperature on Axle Power Losses

    Xu, Hai   Singh, Avinash   Kahraman, Ahmet   Hurley, Joshua   Shon, Sam  

    In order to boost the fuel economy of their vehicles, automotive Original Equipment Manufacturers (OEMs) and suppliers have been investigating a range of options from alternate vehicle propulsion systems down to optimized component level technologies. The hypoid gear set in a rear axle is one of the least efficient drive train components, and as such, provides unique opportunities for improvements. It has therefore attracted significant attention from researchers to reduce the power losses. Both loaded and unloaded power losses have been studied before and found to vary significantly with load and speed conditions. This paper will focus on the effects of the axle pinion bearing preload, axle gear oil levels, and operating temperatures on axle power losses during the fuel economy driving cycles where both axle load and speed vary significantly. In this paper, power loss measurements from experiments conducted on an automotive rear drive axle on a dedicated dynamometer will be presented. Tests were conducted under a range of speed and load conditions that were developed from Environmental Protection Agency (EPA) fuel economy driving cycles. Both urban and highway cycles were included in the tests. Separate tests were conducted for unloaded spin losses and loaded power losses. The tests were conducted at a few different controlled levels of gear oil operating temperatures, gear oil volumes, and pinion bearing preloads, and their influence on power losses was quantified. The measured power losses at a matrix of load and speed conditions provide a series of power loss maps as a function of gear oil operating temperature, oil volume, and bearing preload. Using these power loss maps, the overall axle efficiency or power loss during any driving cycle can be quantified by integrating the instantaneous power losses as the axle goes through the driving cycles. Similar maps can be created for other influences and the proposed procedure can be utilized to quantify their influences on a given driving cycle. Results from this study indicate that with the combination of appropriate preloads, gear oil volume, and temperature control, axle efficiency can potentially be improved by roughly 3% in the tested axle. [DOI:10.1115/1.4006325]
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  • Interfacial Adsorption of Antifreeze Proteins: A Neutron Reflection Study

    Xu, Hai   Perumal, Shiamalee   Zhao, Xiubo   Du, Ning   Liu, Xiang-Yang   Jia, Zongchao   Lu, Jian R.  

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  • Late Holocene Indian summer monsoon variations recorded at Lake Erhai, Southwestern China

    Xu, Hai   Zhou, Xinying   Lan, Jianghu   Liu, Bin   Sheng, Enguo   Yu, Keke   Cheng, Peng   Wu, Feng   Hong, Bin   Yeager, Kevin M.   Xu, Sheng  

    In this study we report changes in Indian summer monsoon (ISM) intensity during the past 3500 yr inferred from proxy indices at Lake Erhai, southwestern China. Both the pollen concentrations and other proxy indices, including sediment grain size, total organic carbon contents (TOC), and elemental contents (e.g., Fe, Al), clearly indicate a long term decreasing trend in ISM intensity over the late Holocene. During the period from approximately AD 750 to AD 1200, pollen concentrations of conifer and broadleaf trees, and herbs reached the lowest levels over the past 3500 yr; while the pollen percentages of both herbs and broadleaf trees increased, suggesting a significant medieval drought. The grain size, TOC, and elemental contents also support an arid climate during the medieval period. The Little Ice Age (LIA) at Lake Erhai was characterized as cold and wet. The medieval and LIA climatic patterns at Lake Erhai were similar to those over most of the ISM areas, but anti-phase with those over East Asian summer monsoon (EASM) areas. We suspect that sea surface temperature variations in the Indo-Pacific oceans and the related land-sea thermal contrasts may be responsible for such hydroclimatic differences between EASM and ISM areas. (C) 2014 University of Washington. Published by Elsevier Inc. All rights reserved.
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  • Differential transformation efficiency of Japonicarice varieties developed in northern China

    Li, Dan   Xu, Hai   Sun, Xiaoxue   Cui, Zhibo   Zhang, Yuan   Bai, Yuguan   Wang, Xiaoxue   Chen, Wenfu  

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  • Deuterated Ethanol as a Probe for Measuring Equilibrium Isotope Effects for Hydroxyl Exchange

    Xu, Hai   Zhao, Siqi   Xiong, Xiang   Yao, Jiayao   Cross, R. James   Saunders, Martin  

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