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Now showing items 33 - 48 of 54
Measurement of the nucleon structure function F(2) in the nuclear medium and evaluation of its moments RID A-2439-2012 RID E-8618-2010 RID B-4083-2012
Osipenko, M. Ricco, G. Simula, S. Ripani, M. Taiuti, M. Adhikari, K. P. Amaryan, M. J. Anghinolfi, M. Avakian, H. Baghdasaryan, H. Battaglieri, M. Batourine, V. Bedlinskiy, I. Biselli, A. S. Branford, D. Briscoe, W. J. Brooks, W. K. Burkert, V. D. Careccia, S. L. Carman, D. S. Cole, P. L. Collins, P. Crede, V. D'Angelo, A. Daniel, A. Dashyan, N. De Vita, R. De Sanctis, E. Deur, A. Dey, B. Dhamija, S. Dickson, R. Djalali, C. Doughty, D. Dupre, R. Egiyan, H. El Alaoui, A. Eugenio, P. Fegan, S. Forest, T. A. Fradi, A. Gabrielyan, M. Y. Gevorgyan, N. Gilfoyle, G. P. Giovanetti, K. L. Gohn, W. Gothe, R. W. Griffioen, K. A. Guo, L. Hafidi, K. Hakobyan, H. Hanretty, C. Hassall, N. Heddle, D. Hicks, K. Holtrop, M. Ilieva, Y. Ireland, D. G. Isupov, E. L. Jawalkar, S. S. Jo, H. S. Joo, K. Keller, D. Khandaker, M. Khetarpal, P. Kim, W. Klein, A. Klein, F. J. Kubarovsky, V. Kuhn, S. E. Kuleshov, S. V. Kuznetsov, V. Livingston, K. Lu, H. Y. Martinez, D. Mayer, M. McAndrew, J. McCracken, M. E. McKinnon, B. Meyer, C. A. Mirazita, M. Mokeev, V. Moreno, B. Moriya, K. Morrison, B. Moutarde, H. Munevar, E. Nadel-Turonski, P. Nasseripour, R. Niccolai, S. Niculescu, I. Ostrovidov, A. I. Paremuzyan, R. Park, K. Park, S. Pasyuk, E. Pereira, S. Anefalos Pisano, S. PogoreIko, O. Pozdniakov, S. Price, J. W. Procureur, S. Prok, Y. Protopopescu, D. Raue, B. A. Rosner, G. Rossi, P. Sabatie, F. Saini, M. S. Salamanca, J. Salgado, C. Saracco, P. Schumacher, R. A. Seraydaryan, H. Sharabian, Y. G. Smith, E. S. Sober, D. Sokhan, D. Stepanyan, S. S. Stepanyan, S. Stoler, P. Strauch, S. Tedeschi, D. J. Tkachenko, S. Ungaro, M. Vernarsky, B. Vineyard, M. F. Voutier, E. Watts, D. P. Weygand, D. P. Wood, M. H. Yegneswaran, A. Zhang, J. Zhao, B.We report on the measurement of inclusive electron scattering off a carbon target performed with CLAS at Jefferson Laboratory. A combination of three different beam energies 1.161, 2.261 and 4.461 GeV allowed us to reach an invariant mass of the final-state hadronic system W approximate to 2.4 GeV with four-momentum transfers Q(2) ranging from 0.2 to 5 (GeV/c)(2). These data, together with previous measurements of the inclusive electron scattering off proton and deuteron, which cover a similar continuous two-dimensional region of Q(2) and Bjorken variable x, permit the study of nuclear modifications of the nucleon structure. By using these, as well as other world data, we evaluated the F(2) structure function and its moments. Using an OPE-based twist expansion, we studied the Q(2)-evolution of the moments, obtaining a separation of the leading-twist and the total higher-twist terms. The carbon-to-deuteron ratio of the leading-twist contributions to the F(2) moments exhibits the well-known EMC effect, compatible with that discovered previously in x-space. The total higher-twist term in the carbon nucleus appears, although with large systematic uncertainties, to be smaller with respect to the deuteron case for n < 7, suggesting partial parton deconfinement in nuclear matter. We speculate that the spatial extension of the nucleon is changed when it is immersed in the nuclear medium. (C) 2010 Elsevier B.V. All rights reserved.
Salgado, C.We report on hadron spectroscopy using the CLAS at Jefferson Lab. We present preliminary results from photoproduction experiments studying the spectroscopy of exotic mesons, cascades (Xi's) and Dalitz decays of pseudo-scalar mesons in the largest data sample ever to be produced at photon energies of about 5 GeV. We also describe, briefly, a new experiment to continue hadron spectroscopy at CLAS12 (at Jefferson Lab energy upgrade) using electroproduction at very low Q 2 ("quasireal photons") up to photon energies of 10 GeV.
Target and double spin asymmetries of deeply virtual pi(0) production with a longitudinally polarized proton target and CLAS
Kim, A. Avakian, H. Burkert, V. Joo, K. Kim, W. Adhikari, K. P. Akbar, Z. Pereira, S. Anefalos Badui, R. A. Battaglieri, M. Batourine, V. Bedlinskiy, I. Biselli, A. S. Boiarinov, S. Bosted, P. Briscoe, W. J. Brooks, W. K. Bultmann, S. Cao, T. Carman, D. S. Celentano, A. Chandavar, S. Charles, G. Chetry, T. Colaneri, L. Cole, P. L. Compton, N. Contalbrigo, M. Cortes, O. Crede, V. D'Angelo, A. Dashyan, N. De Vita, R. De Sanctis, E. Djalali, C. Egiyan, H. El Alaoui, A. El Fassi, L. Eugenio, P. Fedotov, G. Fersch, R. Filippi, A. Fleming, J. A. Fradi, A. Con, M. Garc Ghandilyan, Y. Gilfoyle, G. P. Giovanetti, K. L. Girod, F. X. Gohn, W. Golovatch, E. Gothe, R. W. Griffioen, K. A. Guo, L. Hafidi, K. Hanretty, C. Hattawy, M. Heddle, D. Hicks, K. Holtrop, M. Ilieva, Y. Ireland, D. G. Ishkhanov, B. S. Jenkins, D. Jiang, H. Jo, H. S. Joosten, S. Keller, D. Khachatryan, G. Khandaker, M. Klein, A. Klein, F. J. Kubarovsky, V. Kuhn, S. E. Kuleshov, S. V. Lanza, L. Lenisa, P. Lu, H. Y. MacGregor, I. J. D. Markov, N. Mattione, P. McCracken, M. E. McKinnon, B. Mokeev, V. Movsisyan, A. Munevar, E. Nadel-Turonski, P. Net, L. A. Niccolai, S. Osipenko, M. Ostrovidov, A. I. Paolone, M. Park, K. Pasyuk, E. Phelps, W. Pisano, S. Pogorelko, O. Price, J. W. Prok, Y. Ripani, M. Rizzo, A. Rosner, G. Rossi, P. Roy, P. Salgado, C. Schumacher, R. A. Seder, E. Sharabian, Y. G. Skorodumina, Iu. Smith, G. D. Sokhan, D. Sparveris, N. Stepanyan, S. Stoler, P. Strakovsky, I. I. Strauch, S. Sytnik, V. Taiuti, M. Torayev, B. Ungaro, M. Voskanyan, H. Voutier, E. Watts, D. P. Wei, X. Weinstein, L. B. Zachariou, N. Zana, L. Zhang, J.The target and double spin asymmetries of the exclusive pseudoscalar channel (e) over right arrow(p) over right arrow -> ep pi(0) ere measured for the first time in the deep-inelastic regime using a longitudinally polarized 5.9 GeV electron beam and a longitudinally polarized proton target at Jefferson Lab with the CEBAF Large Acceptance Spectrometer (CLAS). The data were collected over a large kinematic phase space and divided into 110 four-dimensional bins of Q(2), x(B), -t and phi. Large values of asymmetry moments clearly indicate a substantial contribution to the polarized structure functions from transverse virtual photon amplitudes. The interpretation of experimental data in terms of generalized parton distributions (GPDs) provides the first insight on the chiral-odd GPDs (I) over tildeI(T) and E-T, and complement previous measurements of unpolarized structure functions sensitive to the GPDs H-T and (E) over bar (T). These data provide a crucial input for parametrizations of essentially unknown chiral-odd GPDs and will strongly influence existing theoretical calculations based on the handbag formalism. (C) 2017 The Author(s). Published by Elsevier B.V.
Effects of scorpion venom tityustoxin on central nervous system: M. V. Gomez, T. Moraes-Santos, M. A. M. Prado, A. H. I. Salgado, R. S. Gomez, T. A. A. Casali and C. R. Diniz (Department of Pharmacology, ICB, UFMG-Belo Horizonte-MG, Brazil)
Jimenez-Heffernan, A. Gomez-Millan, J. Sanchez De Mora, E. Delgado Moreno, J. Delgado Gil, M. M. Salgado, C. Contreras Puertas, P. Bermudez Morales, M. C. Lopez, J. Paz Exposito, J.Objective: To assess the role of quantitative salivary gland scintigraphy (SGS) in the detection of functional impairment of salivary glands in patients with head and neck cancer treated with radiotherapy (RI). Material and methods: We studied 19 patients (17 men), mean age 62.4 years (44-75). Three studies were performed to each patient: baseline, 3 and 18 months after RT. SGS was acquired for 25 minutes following injection of 3.7 MBq/kg of (99m)Tc-pertechnetate with lemon juice at the end of minute 15. Excretion fraction (EF), counts per minute/pixel/MBq (CMPM) and uptake percentage were obtained from time-activity curves from ROIs placed over parotid (PG) and submandibular glands (SMG) and related to the doses received by the PG. Results: EF showed a significant reduction from the baseline to the 3 months study (p < 0.001) for the PG and SMG and from the baseline to the 18 months study for the SMG (p < 0.001). A significant improvement of EF was seen from the 3 months to the 18 months study for the PG (p < 0.05). CMPM did not change significantly from the baseline to the 3 months and 18 months studies for the PG and showed a significant reduction (p < 0.01) for the SMG from the baseline to 18 months study. The uptake percentage did not change significantly between studies. A moderate association was observed between the doses to PG and the 3 m study parameters. Conclusions: EF was more sensitive than uptake in assessing post-RT impairment of salivary function. In addition, it reflected functional recovery of parotid glands over time. (C) 2009 Elsevier Espana, S.L. and SEMNIM. All rights reserved.
Generation of high energy laser-driven electron and proton sources with the 200 TW system VEGA 2 at the Centro de Laseres Pulsados
Volpe, L. Fedosejevs, R. Gatti, G. Perez-Hernandez, J. A. Mendez, C. Apinaniz, J. Vaisseau, X. Salgado, C. Huault, M. Malko, S. Zeraouli, G. Spina, V Longman, A. De Luis, D. Li, K. Varela, O. Garcia, E. Hernandez, I Pisonero, J. D. Garcia Ajates, J. Alvarez, J. M. Garcia, C. Rico, M. Arana, D. Hernandez-Toro, J. Roso, L.The Centro de Laseres Pulsados in Salamanca, Spain has recently started operation phase and the first user access period on the 6 J 30 fs 200 TW system (VEGA 2) already started at the beginning of 2018. In this paper we report on two commissioning experiments recently performed on the VEGA 2 system in preparation for the user campaign. VEGA 2 system has been tested in different configurations depending on the focusing optics and targets used. One configuration (long focal length F =3D 130 cm) is for underdense laser-matter interaction where VEGA 2 is focused onto a low density gas-jet generating electron beams (via laser wake field acceleration mechanism) with maximum energy up to 500 MeV and an X-ray betatron source with a 10 keV critical energy. A second configuration (short focal length F =3D 40 cm) is for overdense laser-matter interaction where VEGA 2 is focused onto a 5 mu m thick Al target generating a proton beam with a maximum energy of 10 MeV and temperature of 2.5 MeV. In this paper we present preliminary experimental results.
Measurement of the x- and Q(2)-dependence of the asymmetry A(1) on the nucleon RID A-2074-2012 RID E-8618-2010 RID B-4083-2012
Dharmawardane, K. V. Kuhn, S. E. Bosted, P. Prok, Y. Adams, G. Ambrozewicz, P. Anghinolfi, M. Asryan, G. Avakian, H. Bagdasaryan, H. Baillie, N. Ball, J. P. Baltzell, N. A. Barrow, S. Batourine, V. Battaglieri, M. Beard, K. Bedlinskiy, I. Bektasoglu, M. Bellis, M. Benmouna, N. Biselli, A. S. Bonner, B. E. Bouchigny, S. Boiarinov, S. Bradford, R. Branford, D. Brooks, W. K. Bultmann, S. Burkert, V. D. Butuceanu, C. Calarco, J. R. Careccia, S. L. Carman, D. S. Carnahan, B. Cazes, A. Chen, S. Cole, P. L. Collins, P. Coltharp, P. Cords, D. Corvisiero, P. Crabb, D. Crannell, H. Crede, V. Cummings, J. P. De Masi, R. DeVita, R. De Sanctis, E. Degtyarenko, P. V. Denizli, H. Dennis, L. Deur, A. Djalali, C. Dodge, G. E. Donnelly, J. Doughty, D. Draigovitsch, P. Dugger, M. Dytman, S. Dzyubak, O. P. Egiyan, H. Egiyan, K. S. Elouadrhiri, L. Eugenio, P. Fatemi, R. Fedotov, G. Feuerbach, R. J. Forest, T. A. Funsten, H. Garcon, M. Gavalian, G. Gilfoyle, G. P. Giovanetti, K. L. Girod, F. X. Goetz, J. T. Golovatch, E. Gonenc, A. Gothe, R. W. Griffioen, K. A. Guidal, M. Guillo, M. Guler, N. Guo, L. Gyurjyan, V. Hadjidakis, C. Hafidi, K. Hakobyan, R. S. Hardie, J. Heddle, D. Hersman, F. W. Hicks, K. Hleiqawi, I. Holtrop, M. Huertas, M. Hyde-Wriyht, C. E. Ilieva, Y. Ireland, D. G. Ishkhanov, B. S. Isupov, E. L. Ito, M. M. Jenkins, D. Jo, H. S. Joo, K. Juengst, H. G. Keith, C. Kellie, J. D. Khandaker, M. Kim, K. Y. Kim, K. Kim, W. Klein, A. Klein, F. J. Klusman, M. Kossov, M. Kramer, L. H. Kubarovsky, V. Kuhn, J. Kuleshov, S. V. Lachniet, J. Laget, J. M. Langheinrich, J. Lawrence, D. Li, Ji Lima, A. C. S. Livingston, K. Lu, H. Lukashin, K. MacCormick, M. Manak, J. J. Markov, N. McAleer, S. McKinnon, B. McNabb, J. W. C. Mecking, B. A. Mestayer, M. D. Meyer, C. A. Mibe, T. Mikhailov, K. Minehart, R. Mirazita, M. Miskimen, R. Mokeev, V. Morand, L. Morrow, S. A. Moteabbed, M. Mueller, J. Mutchler, G. S. Nadel-Turonski, P. Napolitano, J. Nasseripour, R. Niccolai, S. Niculescu, G. Niculescu, I. Niczyporuk, B. B. Niroula, M. R. Nyazov, R. A. Nozar, M. O'Rielly, G. V. Osipenko, M. Ostrovidov, A. I. Park, K. Pasyuk, E. Paterson, C. Philips, S. A. Pierce, J. Pivnyuk, N. Pocanic, D. Pogorelko, O. Polli, E. Pozdniakov, S. Preedom, B. M. Price, J. W. Protopopescu, D. Qin, L. M. Raue, B. A. Riccardi, G. Ricco, G. Ripani, M. Ritchie, B. G. Ronchetti, F. Rosner, G. Rossi, P. Rowntree, D. Rubin, P. D. Sabatie, E. Salgado, C. Santoro, J. P. Sapunenko, V. Schumacher, R. A. Serov, V. S. Sharabian, Y. G. Shaw, J. Shvedunov, N. V. Skabelin, A. V. Smith, E. S. Smith, L. C. Sober, D. I. Stavinsky, A. Stepanyan, S. S. Stepanyan, S. Stokes, B. E. Stoler, P. Strakovsky, I. I. Strauch, S. Suleiman, R. Taiuti, M. Taylor, S. Tedeschi, D. J. Thoma, U. Thompson, R. Tkabladze, A. Tkachenko, S. Todor, L. Tur, C. Ungaro, M. Vineyard, M. F. Vlassov, A. V. Weinstein, L. B. Weygand, D. P. Williams, M. Wolin, E. Wood, M. H. Yegneswaran, A. Yun, J. Zana, L. Zhang, J. Zhao, B. Zhao, Z.We report results for the virtual photon asymmetry A I on the nucleon from new Jefferson Lab measurements. The experiment, which used the CEBAF Large Acceptance Spectrometer and longitudinally polarized proton ((NH3)-N-15) and deuteron ((ND3)-N-15) targets, collected data with a longitudinally polarized electron beam at energies between 1.6 GeV and 5.7 GeV. In the present. Letter, we concentrate on our results for A(1) (x, Q(2)) and the related ratio g(1)/F-1 (x, Q(2))) in the resonance and the deep inelastic regions for our J west and highest beam energies, covering a range in momentum transfer Q(2) from 0.05 to 5.0 (GeV/c)(2) and in final-state invariant mass W up to about 3 GeV. Our data show detailed structure in the resonance re-ion, which leads to a strong Q(2) dependence of A(1) (x, Q(2)) to. W below 2 GeV. At higher W, a smooth approach to the scaling limit, established by earlier experiments, can be seen, but A I (x, Q(2)) is not strictly Q(2)-independent. We add significantly to the world data set at high x, up to x = 0.6. Our data exceed the SU(6)-symmetric quark model expectation for both the proton and the deuteron while being consistent with a negative d-quark polarization up to our highest x. This data set should improve next-to-leading order (NLO) pQCD fits of the parton polarization distributions. (c) 2006 Elsevier B.V.All rights reserved.
Accumulation and transformation of DSP toxins in mussels Mytilus galloprovincialis during a toxic episode caused by Dinophysis acuminata.
Arevalo, F. Fernandez, M. L. Maneiro, J. Pazos, Y. Salgado, C. Blanco, J.The time course of several outbreaks of the diarrhetic shellfish poisoning (DSP) producer Dinophysis acuminata and the consequent kinetic of accumulation and loss of toxins in mussels Mytilus galloprovincialis feeding on them was studied. Samples of mussels and seawater were frequently (2-3 times a week) collected from a raft in the Ria de Vigo. DSP toxins content of mussels and water was analyzed by HPLC-FD and phytoplankton was quantified in an inverted light microscope. Only okadaic acid (OA) and some of its conjugated forms (OA CF), estimated by enzymatic hydrolysis, were found in the plankton samples obtained, comprised mainly of D. acuminata cells. The main accumulated form in mussels was OA reaching a maximum of 10.1 mug OA g-1 in the digestive gland (d.g.) in 16 days, falling below the quarantine level (ca. 2 mug OA g-1 d.g.) by 45 days. The low polarity conjugated forms (LPCF), estimated by hexane extraction, accounted for 6.2% of the total toxin burden of the mussels. To quantify the rates of the processes involved in the accumulation, transformation and loss of the toxins, two dynamic models, a one-compartment and a two-compartment, including OA and its conjugated forms as variables were designed and implemented. The one-compartment model provided a good fit to the OA and LPCF actual data (r2=0.92 and r2=0.94, respectively). The two-compartment model did not fit the data markedly better than its one-compartment counterpart (r2=0.93 and r2=0.95, for OA and LPCF, respectively). High hydrolysis rates were estimated for most of the OA CF, which means that these forms came largely from the ingested plankton. The low estimated acylation rates support the previous point and suggest that the formation of LPCF by direct acylation of the OA is of little importance in M. galloprovincialis. Only in cases where the intoxication period is very long, can the formed acyl-derivatives be important, because they seem to accumulate for a long time in the mussels, as suggested by the low hydrolysis and depuration rates estimated from model fitting.
Fouling study of nanofiltration membranes for sugar control in grape must:Analysis of resistances and the role of osmotic pressure
Salgado, C. Carmona, F. J. Palacio, L. Hernandez, A. Pradanos, P.Three membranes are analyzed attending to their retention, flux, and fouling when used to nanofiltrate sugars in red grape musts. In the presence of high molecular weight compounds, that is, when filtering must, fouling develops from initial pore blocking to final cake deposition. A decrease of resistance appears due to a decrease of the effective transmembrane pressure and cake compaction. The final effective pore size corresponds to that of the compacted cake. Attending to flux decay and sugar retention, two membranes, HL and SR3, are appropriate to reduce the content of sugar of red must. Specifically SR3 shows the best passage of sugar and less fouling.
Salgado, C. Da Costa, G. S. Yong, D. Norris, J. E.Recent studies of the Milky Way and its satellites have paid special attention to the importance of carbon-enhanced metal-poor (CEMP) stars due to their involvement in Galactic formation history and their possible connection with the chemical elements originating in the first stellar generation. In an ongoing study of red giants in the Sculptor dwarf galaxy, we have discovered a star with extremely strong CN and CH molecular bands. This star, Scl-1013644, has previously been identified by Geisler et al. as a star with an enrichment in the heavy elements. Spectrum synthesis has been used to derive the carbon, nitrogen and barium abundances for Scl-1013644. Our findings are [C/Fe] =3D +0.8, [N/Fe] =3D -0.3 and [Ba/Fe] =3D +2.1 with the latter result consistent with the value found by Geisler et al. These results reveal Scl-1013644 as a CEMP-s star, the third such star discovered in this dwarf galaxy.
Severe Anemia From Parvovirus B19 Infection in Pediatric Renal Transplant Recipients: Two Case Reports
Grandy, J. Zambrano, P. Corta, B. Salas, P. Salgado, I. Santander, J. Salgado, C. Chadid, J. Iniguez, R.Human parvovirus B19 (PVB19) is the etiologic agent of erythema infectiosum (fifth disease), a common childhood exanthema. Immunocompromised patients risk developing chronic infections leading to pure red blood cell aplasia. Herein we have reported our experience with two pediatric renal transplant recipients who had severe pure red cell aplasia in the early period after surgery, accompanying PVB19 infection.First Case. A 6-year-old boy underwent pro emptive living-related renal transplantation in September 2006. On day 4, he developed abdominal discomfort and diarrhea. After transplantation, he began an asymptomatic drop in hematocrit without reticulocytosis, which was unresponsive to recombinant erythropoietin. Diarrhea also persisted. Polymerase chain reaction (PCR) was positive for cytomegalovirus (CMV) in the gastrointestinal tract. PVB19 was confirmed by PCR on a bone marrow sample. He was transfused with packed red cells and treated with ganciclovir and intravenous immunoglobulin (IVIG). His hematocrit increased and diarrhea ended. Six months later anemia recurred requiring a second infusion of IVIG. Subsequently he has done well.Second Case. A 15-year-old boy received a living-related renal transplant in October 2006, after 2 years on automated peritoneal dialysis. One month later he developed a progressive, nonregenerative anemia. A bone marrow aspirate confirmed a PVB19 infection by PCR. He received a blood transfusion and IVIG with a favorable response.Conclusions. The presence of persistent anemia in immunocompromised hosts with a low reticulocyte count suggests PVB19 infection. WIG therapy is effective to treat chronic PVB19 infections.
Ambrozewicz, P. Ye, L. Prok, Y. Larin, I Ahmidouch, A. Baker, K. Baturin, V Benton, L. Bernstein, A. Burkert, V Clinton, E. Cole, P. L. Collins, P. Dale, D. Danagoulian, S. Davidenko, G. Demirchyan, R. Deur, A. Dolgolenko, A. Dutta, D. Dzyubenko, G. Evdokimov, A. Fedotov, G. Feng, J. Gabrielyan, M. Gan, L. Gao, H. Gasparian, A. Gevorkyan, N. Gevorkyan, S. Glamazdin, A. Goryachev, V Guo, L. Gyurjyan, V Hardy, K. He, J. Isupov, E. Ito, M. M. Jiang, L. Kang, H. Kashy, D. Khandaker, M. Kingsberry, P. Klein, F. Kolarkar, A. Konchatnyi, M. Korchin, O. Korsch, W. Kosinov, O. Kowalski, S. Kubantsev, M. Kubarovsky, A. Kubarovsky, V Lawrence, D. Li, X. Levillain, M. Lu, H. Ma, L. Martel, P. Matveev, V McNulty, D. Mecking, B. Micherdzinska, A. Milbrath, B. Minehart, R. Miskimen, R. Mochalov, V Morrison, B. Mtingwa, S. Nakagawa, I Overby, S. Pasyuk, E. Payen, M. Park, K. Pedroni, R. Phelps, W. Protopopescu, D. Rimal, D. Ritchie, B. G. Romanov, D. Salgado, C. Shahinyan, A. Sitnikov, A. Sober, D. Stepanyan, S. Stephens, W. Tarasov, V Taylor, S. Teymurazyan, A. Underwood, J. Vasiliev, A. Vishnyakov, V. Weygand, D. P. Wood, M. Zhang, Y. Zhou, S. Zihlmann, B.The cross section of atomic electron Compton scattering gamma + e -> gamma' + e' was measured in the 4.400-5.475 GeV photon beam energy region by the PrimEx collaboration at Jefferson Lab with an accuracy of 2.6% and less. The results are consistent with theoretical predictions that include next-to-leading order radiative corrections. The measurements provide the first high precision test of this elementary QED process at beam energies greater than 0.1 GeV. (C) 2019 The Author(s). Published by Elsevier B.V.
Inter-laboratory validation of the fluorescent protein phosphatase inhibition assay to determine diarrhetic shellfish toxins: Intercomparison with liquid chromatography and mouse bioassay
Gonzalez, J. C. Leira, F. Fontal, O. I. Vieytes, M. R. Arevalo, F. F. Vieites, J. M. Bermudez-Puente, M. Muniz, S. Salgado, C. Yasumoto, T. Botana, L. M.Toxic episodes of diarrhetic shellfish toxins (DSP) in shellfish harvesting areas have serious economic and public health implications, where fluorescent protein phosphatase inhibition assay (FPPIA) may be a highly useful tool for monitoring purposes. This paper presents results from the first inter-laboratory study to validate the assay. Three laboratories participated in the design and development of the inter-laboratory work. Standard solutions and spiked samples of the main toxin, okadaic acid, were used at the beginning of the validation exercise to avoid cross-inhibition of other toxins that would otherwise deteriorate the quantitative significance of the data. HPLC with fluorimetric detection of okadaic acid was also submitted to inter-laboratory validation to be subsequently used as a quantitative reference method. FPPIA results from spiked samples were free of systematic bias in any laboratory and determinations repeated over 3 days showed that the classic "repeatability" was the main within-laboratory source of variability (15-26% R.S.D. depending on the sample). After the inter-laboratory validation of both HPLC and FPPIA methods, 83 samples of mussel hepatopancreas collected during a toxic DSP episode were analyzed over 9 weeks. Toxic levels determined with FPPIA were in line with mouse bioassay results, highlighting the lack of false negative results of the FPPIA test: 98.7% of samples whose concentration of okadaic acid equivalents was over 0.8 mug/g hep., provided positive bioassay results within 24 h of observation time. The reliability and the quantitativeness of the FPPIA method in naturally contaminated samples was demonstrated by intercomparison with mouse bioassay and HPLC.
Influence of low and high molecular weight compounds on the permeate flux decline in nanofiltration of red grape must
Salgado, C. Palacio, L. Carmona, F.J. Hernández, A. Prádanos, P.The influence of both low and high molecular weight compounds present in red grape must in the decline of permeate flux (J(v)) during its nanofiltration was studied. The most important low molecular weight compounds are glucose and fructose while other compounds, such as polyphenols, polysaccharides, proteins etc. have high molecular weight. A synthetic solution containing the typical low molecular weight compounds of natural must was nanofiltered and the results compared with those obtained by the nanofiltration of commercial red must. During nanofiltration of red must a gel layer was formed and thickened on the membrane surface leading to a rapid decrease in J(v) and a slow increase of the concentration of sugars in the retentate due to the small permeate volume recovery. A method was proposed to allow studying individually the resistances and fouling mechanism generated by sugars and high molecular weight solutes under these extreme conditions. Results showed that high molecular weight compounds have more influence on the permeate flux decrease since they are mainly responsible for the fouling phenomenon (cake filtration fouling mechanism), while low molecular weight compounds contribute to the flux decay mostly through an increase of the osmotic pressure during the process. (C) 2012 Elsevier B.V. All rights reserved.
Qian, X. Chen, W. Gao, H. Hicks, K. Kramer, K. Laget, J. M. Mibe, T. Qiang, Y. Stepanyan, S. Tedeschi, D. J. Xu, W. Adhikari, K. P. Amaryan, M. Anghinolfi, M. Ball, J. Battaglieri, M. Batourine, V. Bedlinskiy, I. Bellis, M. Biselli, A. S. Bookwalter, C. Branford, D. Briscoe, W. J. Brooks, W. K. Burkert, V. D. Careccia, S. L. Carman, D. S. Cole, P. L. Collins, P. Crede, V. D'Angelo, A. Daniel, A. Dashyan, N. De Vita, R. De Sanctis, E. Deur, A. Dey, B. Dhamija, S. Djalali, C. Doughty, D. Dupre, R. Egiyan, H. El Alaoui, A. Eugenio, P. Fegan, S. Gabrielyan, M. Y. Gevorgyan, N. Gilfoyle, G. P. Giovanetti, K. L. Girod, F. X. Goetz, J. T. Gohn, W. Gothe, R. W. Graham, L. Griffioen, K. A. Guidal, M. Guo, L. Hafidi, K. Hakobyan, H. Hanretty, C. Hassall, N. Holtrop, M. Ilieva, Y. Ireland, D. G. Jawalkar, S. S. Jo, H. S. Joo, K. Keller, D. Khandaker, M. Khetarpal, P. Kim, A. Kim, W. Klein, A. Klein, F. J. Konczykowski, P. Kubarovsky, V. Kuleshov, S. V. Kuznetsov, V. Livingston, K. Martinez, D. Mayer, M. McAndrew, J. McCracken, M. E. McKinnon, B. Meyer, C. A. Mikhailov, K. Mineeva, T. Mirazita, M. Mokeev, V. Moreno, B. Moriya, K. Morrison, B. Moutarde, H. Munevar, E. Nadel-Turonski, P. Ni, A. Niccolai, S. Niculescu, I. Niroula, M. R. Osipenko, M. Ostrovidov, A. I. Paremuzyan, R. Park, K. Park, S. Pereira, S. Anefalos Pisano, S. Pogorelko, O. Pozdniakov, S. Price, J. W. Procureu, S. Protopopescu, D. Ricco, G. Ripani, M. Ritchie, B. G. Rosner, G. Rossi, P. Sabatie, F. Saini, M. S. Salgado, C. Schott, D. Schumacher, R. A. Seder, E. Seraydaryan, H. Sharabian, Y. G. Smith, E. S. Smith, G. D. Sober, D. I. Sokhan, D. Stepanyan, S. S. Stoler, P. Strakovsky, I. I. Strauch, S. Taiuti, M. Taylor, C. E. Tkachenko, S. Ungaro, M. Vernarsky, B. Vineyard, M. F. Voutier, E. Weinstein, L. B. Weygand, D. P. Wood, M. H. Zachariou, N. Zana, L. Zhang, J. Zhao, B. Zhao, Z. W.We report the first, kinematically-complete measurement of the differential cross section of phi-meson photoproduction from deuterium near the production threshold for a proton using the CLAS detector and a tagged-photon beam in Hall B at Jefferson Lab. The measurement was carried out by a triple coincidence detection of a proton, K+ and K- near the theoretical production threshold of 1.57 GeV. The extracted differential cross sections d sigma/dt for the initial photon energy range of 1.65-1.75 GeV are consistent with predictions based on a quasifree mechanism. Our finding is different from recent LEPS results on phi-meson photoproduction from deuterium in a similar incident photon energy range, but in a different momentum transfer region. (C) 2011 Elsevier B.V. All rights reserved.
Prospective evaluation of a model of prediction of invasive bacterial infection risk among children with cancer, fever, and neutropenia
Santolaya, M. E. Alvarez, A. M. Aviles, C. L. Becker, A. Cofre, J. Enriquez, N. O'Ryan, M. Paya, E. Salgado, C. Silva, P. Tordecilla, J. Varas, M. Villarroel, M. Viviani, T. Zubieta, M.A risk prediction model for invasive bacterial infection (IBI) was prospectively evaluated among children presenting with cancer, fever, and neutropenia. The model incorporated assessment of 5 previously identified risk factors: serum level of C-reactive protein (CRP) gtoreq90 mg/L, hypotension, identification of relapse of leukemia as the cancer type, platelet count of ltoreq50,000 platelets/mm3, and recent receipt of chemotherapy (16). Children were uniformly evaluated at enrollment and were classified as having high or low risk for IBI according to a model that considers the number and type of variables present. Of the 263 febrile episodes evaluated during a 17-month period, 140 (53%) were in IBI-positive children. The sensitivity, specificity, and positive and negative predictive values of the model were 92%, 76%, 82%, and 90%, respectively. Identification of these 5 risk factors during the first 24 h of hospitalization was helpful in discriminating between children with a high or low risk for IBI.