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Now showing items 1 - 16 of 18

  • Esistenza ed Essere (L\"Uomo e la Conoscenza)by Enrico Nicoletti

    Review by: J. de Finance  

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  • Beach nourishment using sediments from relict sand deposit: Effects on subtidal macrobenthic communities in the Central Adriatic Sea (Eastern Mediterranean Sea-Italy)

    Targusi, M.   La Porta, B.   Lattanzi, L.   La Valle, P.   Loia, M.   Paganelli, D.   Pazzini, A.   Proietti, R.   Nicoletti, L.  

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  • —to: Nicoletti F, Conget L, Di Mauro M et al. (2002) Serum concentrations of the interferon-a-inducible chemokine IP-10/CXCL10 are augmented in both newly-diagnosed Type I diabetes mellitus patients

    M. Rotondi   P. Romagnani   A. Brozzetti   F. Santeusanio   M. Serio   A. Falorni A1  

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  • New prodrug of 7-chlorokynurenic acid: Ippolito R., Arenare L., Battaglia G., Nicoletti F. and de Caprariis P. Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli “Federico II”, via D.Montesano 49, 80131-Napoli

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  • —to: Nicoletti F, Conget L, Di Mauro M et al. (2002) Serum concentrations of the interferon-α-inducible chemokine IP-10/CXCL10 are augmented in both newly-diagnosed Type I diabetes mellitus patients and subjects at risk of developing the disease. Diabetologia 45:1107–1110

    M. Rotondi   P. Romagnani   A. Brozzetti   F. Santeusanio   M. Serio   A. Falorni  

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  • The GerdQ questionnaire and high resolution manometry support the hypothesis that proton pump inhibitor-responsive oesophageal eosinophilia is a GERD-related phenomenon

    Savarino, E. V.   Tolone, S.   Bartolo, O.   de Cassan, C.   Caccaro, R.   Galeazzi, F.   Nicoletti, L.   Salvador, R.   Martinato, M.   Costantini, M.   Savarino, V.  

    BackgroundLittle is known about the relationship between proton pump inhibitor-responsive oesophageal eosinophilia (PPI-REE), eosinophilic esophagitis (EoE) and gastro-oesophageal reflux disease (GERD). AimTo compare high resolution manometry features and symptom profiles of patients with EoE, PPI-REE and GERD. MethodsConsecutive patients diagnosed with EoE or PPI-REE according to international criteria (presence of at least one typical symptom of oesophageal dysfunction; at least 15 eosinophils per high-power field at mid/proximal oesophagus, persistence or resolution of eosinophils after an 8-week PPI trial), and a group of patients with proven GERD and oesophageal eosinophilia, prospectively completed the GerdQ questionnaire and underwent high resolution manometry. ResultsThirty-five patients with EoE, 17 with PPI-REE and 27 with GERD were enrolled. When compared to GERD, both EoE and PPI-REE had higher rates of dysphagia (15% vs. 94% vs. 88%, P<0.0001), patients with EoE reported heartburn and regurgitation less frequently (26% vs. 85%, and 17% vs. 74%, respectively; P < 0.001 for each and had lower GerdQ score [1 (0-6) vs. 8 (6-12), P<0.001] than GERD patients. There was no significant difference comparing PPI-REE and GERD patients. Patients with PPI-REE had a higher prevalence of erosive oesophagitis than patients with EoE (35% vs. 9%, P=3D0.04), which was similar to that of GERD (48%, P=3D0.54). Patients with EoE had a lower frequency of high resolution manometry features associated with GERD than patients with PPI-REE. There was no significant difference between PPI-REE and GERD patients. ConclusionGERD, as assessed by GerdQ and high resolution manometry is common in patients with PPI-REE, which may share similar pathogenic mechanisms.
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  • Measurement of eta photoproduction on the proton from threshold to 1500 MeV RID B-1239-2012 RID A-2439-2012

    Bartalini, O.   Bellini, V.   Bocquet, J. P.   Calvat, P.   Capogni, M.   Casano, L.   Castoldi, M.   D'Angelo, A.   Didelez, J.-P.   Di Salvo, R.   Fantini, A.   Franco, D.   Gaulard, C.   Gervino, G.   Ghio, F.   Giardina, G.   Girolami, B.   Giusa, A.   Guidal, M.   Hourany, E.   Kunne, R.   Lapik, A.   Sandri, P. Levi   Lleres, A.   Mammoliti, F.   Mandaglio, G.   Moricciani, D.   Mushkarenkov, A. N.   Nedorezov, V.   Nicoletti, L.   Perrin, C.   Randieri, C.   Rebreyend, D.   Renard, F.   Rudnev, N.   Russew, T.   Russo, G.   Schaerf, C.   Sperduto, M.-L.   Sutera, M.-C.   Turinge, A.   Vegna, V.  

    Beam asymmetry and differential cross-section for the reaction gamma p -> eta p were measured from production threshold to 1500MeV photon laboratory energy. The two dominant neutral decay modes of the eta-meson, eta -> 2 gamma and eta -> 3 pi(0) , were analyzed. The full set of measurements is in good agreement with previously published results. Our data were compared with three models. They all fit satisfactorily the results but their respective resonance contributions are quite different. The possible photoexcitation of a narrow state N(1670) was investigated and no evidence was found.
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  • Application of biotic and taxonomic distinctness indices in assessing the Ecological Quality Status of two coastal lakes: Caprolace and Fogliano lakes (Central Italy)

    Prato, S.   Morgana, J. G.   La Valle, P.   Finoia, M. G.   Lattanzi, L.   Nicoletti, L.   Ardizzone, G. D.   Izzo, G.  

    Marine biotic indices (AMBI, BENTIX) and the statistical tool M-AMBI (Multivariate AMBI) were applied as a comparative approach in assessing the Ecological Quality Status (EcoQS) of two Mediterranean coastal lakes (Caprolace and Fogliano lakes) situated in the Circeo National Park (Central Italy). The macrobenthic community was analysed using univariate indices (community structure), correspondence analysis (CA) and taxonomic distinctness indices (Delta(+) and Lambda(+)). The community composition showed a dominance of lagoonal species in both coastal lakes, while in Caprolace lake marine taxa were also found. Diversity index (H') complies to ranges found in Mediterranean lagoons and taxonomic distinctness indices demonstrated that taxonomy structure is in accordance with natural variability ranges. Principal component analysis (PCA) on chemical parameters of water and sediment showed that both coastal lakes differ mainly in their organic matter composition. In fact, the protein fraction of bio-polymeric carbon prevails in Fogliano lake, while the 'refractory' component represented by carbohydrate fraction is predominant in Caprolace lake. The difference between the two coastal lakes was also demonstrated by co-inertia analysis (COIA) performed using abundance of species and concentrations of chemical parameters. The results from the application of the three biotic indices do not highlight a clear distinction between the two lagoons. However, the AMBI index provided a more suitable evaluation of EcoQS corresponding to 'slightly polluted' lagoons while M-AMBI and moreover BENTIX indices indicated a worsening situation. The biotic indices are widely used in assessing the EcoQS in marine environments, but their proper application in transitional waters would depend on a resettlement; thresholds established in the biotic index scale values need to be modified according to natural variability of transitional waters referring to abiotic conditions and abundance of tolerant species. (C) 2008 Elsevier Ltd. All rights reserved.
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  • Polarization observable measurements for gamma p -> K+ Lambda and gamma p -> K+ Sigma(0) for energies up to 1.5 GeV RID B-1239-2012

    Lleres, A.   Bartalini, O.   Bellini, V.   Bocquet, J. P.   Calvat, P.   Capogni, M.   Casano, L.   Castoldi, M.   D'Angelo, A.   Didelez, J. -P.   Di Salvo, R.   Fantini, A.   Gaulard, C.   Gervino, G.   Ghio, F.   Girolami, B.   Giusa, A.   Guidal, M.   Hourany, E.   Kouznetsov, V.   Kunne, R.   Lapik, A.   Sandri, P. Levi   Moricciani, D.   Mushkarenkov, A. N.   Nedorezov, V.   Nicoletti, L.   Perrin, C.   Randieri, C.   Rebreyend, D.   Renard, F.   Rudnev, N.   Russew, T.   Russo, G.   Schaerf, C.   Sperduto, M. -L.   Sutera, M. -C.   Turinge, A.  

    Beam asymmetries and hyperon recoil polarizations for the reactions gamma p --> K+ Lambda and gamma p --> K+ Sigma(0) have been measured from the threshold production to 1500 MeV with the GRAAL facility located at the ESRF in Grenoble. These results complement the database for the beam asymmetry, covering for the first time the production threshold region. Recent theoretical analyses are presented for which the beam asymmetry data bring interesting new information and allow to better determine some resonance parameters. Most importantly, these results strengthen the need of a new D-13 state around 1900 MeV.
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  • to: Nicoletti F, Conget L, DiMauro M et al. (2002) - Serum concentrations of the interferon-alpha-inducible chemokine IP-10/CXCL10 are augmented in both newly-diagnosed Type 1 diabetes mellitus patients and subjects at risk of developing the disease. RID E-5747-2011

    Rotondi, M   Romagnani, P   Brozzetti, A   Santeusanio, F   Serio, M   Falorni, A  

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  • Beach nourishment using sediments from relict sand deposit:Effects on subtidal macrobenthic communities in the Central Adriatic Sea (Eastern Mediterranean Sea-Italy)

    Targusi, M.   La Porta, B.   Lattanzi, L.   La Valle, P.   Loia, M.   Paganelli, D.   Pazzini, A.   Proietti, R.   Nicoletti, L.  

    Nowadays nourishment is the most popular shore reconstruction strategy to counteract erosion of coastal areas. Sediments used for nourishment can have terrestrial or marine origin. This study analysed the effects of nourishment with relict sand on the subtidal macrobenthic communities and on the surface sediment at 7 sites of the Marche Region (Central Adriatic Sea, Italy). Samples for biological and physical analyses were collected in each site before and after nourishment. One year after nourishment the presence of the relict sands used for the replenishment is still visible in the sediment of each site. In the same period macrobenthic communities are characterised by the dominance of a few species able to avoid burial and suffocation phenomena, showing a low variability respect to the communities present before.
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  • Results from the Graal experiment

    Bartalini, O.   Capogni, M.   D'Angelo, A.   Moricciani, D.   Schaerf, C.   Gaulard, C.   Sandri, P.L.   Anghinolfi, M.   Battaglieri, M.   Castoldi, M.   Corvisiero, P.   Ripani, M.   Sanzone, M.   Taiuti, M.   Zucchiatti, A.   Bellini, V.   Sutera, C.   Bocquet, J.P.   Lleres, A.   Nicoletti, L.   Rebreyend, D.   Renard, F.   Didelez, J.P.   Guidal, M.   Jeicic, A.   Hourany, E.   Ghio, F.   Girolami, B.   Kilvington, I.   Lapik, A.   Kouznetsov, V.   Nedorezov, V.   Turinge, A.   Rudnev, N.  

    The features of the Graal experiment at ESRF are presented. The obtained results are discussed and future developments outlined. The Graal experiment started data taking in 1997. It was run for one year with the green laser line giving rise to a photon beam of maximum energy of 1100 MeV and for one year with UV multi-line and the corresponding gamma-ray beam of 1470 MeV maximum energy. Asymmetry data and cross sections have been produced for eta, pi 0 and pi + photoproduction channels providing, for these reactions, the most extended and coherent data base available until now. Future developments of the experiment will include the study of the same channels with deuteron target and the study of the photoreaction mechanism on the quasi-free neutron. The use of a polarised target of new concept will allow to access double polarisation observables for meson photoproduction on polarised proton and polarised neutron. Finally the increase in the maximum photon energy, up to 1.8 GeV will allow to study in details eta' photoproduction and to reach the threshold for scalar mesons production
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  • New prodrug of 7-chlorokynurenic acid: Ippolito R., Arenare L., Battaglia G., Nicoletti F. and de Caprariis P. Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli “Federico II”, via D.Montesano 49, 80131-Napoli

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  • Measurement of beam-recoil observables O(x), O(z) and target asymmetry T for the reaction gamma p -> K(+)Lambda

    Lleres, A.   Bartalini, O.   Bellini, V.   Bocquet, J. P.   Calvat, P.   Capogni, M.   Casano, L.   Castoldi, M.   D'Angelo, A.   Didelez, J. -P.   Di Salvo, R.   Fantini, A.   Franco, D.   Gaulard, C.   Gervino, G.   Ghio, F.   Girolami, B.   Giusa, A.   Guidal, M.   Hourany, E.   Kunne, R.   Kuznetsov, V.   Lapik, A.   Sandri, P. Levi   Mammoliti, F.   Mandaglio, G.   Moricciani, D.   Mushkarenkov, A. N.   Nedorezov, V.   Nicoletti, L.   Perrin, C.   Randieri, C.   Rebreyend, D.   Renard, F.   Rudnev, N.   Russew, T.   Russo, G.   Schaerf, C.   Sperduto, M. -L.   Sutera, M. -C.   Turinge, A.   Vegna, V.  

    The double polarization (beam-recoil) observables O(x) and O(z) have been measured for the reaction gamma p -> K(+) Lambda from threshold production to E gamma similar to 1500 MeV. The data were obtained with the linearly polarized beam of the GRAAL facility. Values for the target asymmetry T could also be extracted despite the use of an unpolarized target. Analyses of our results by two isobar models tend to confirm the necessity to include new or poorly known resonances in the 1900 MeV mass region.
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  • New experimental and simulated results on nuclear media effects in meson photoproduction off nuclei RID B-1239-2012 RID A-2439-2012

    Ignatov, A.   Bartalini, O.   Bellini, V.   Bocquet, J. P.   Calvat, P.   Capogni, M.   Casano, M.   Castoldi, M.   D'Angelo, A.   Didelez, J. -P.   Di Salvo, R.   Fantini, A.   Gervino, G.   Ghio, F.   Girolami, B.   Giusa, A.   Guidal, M.   Hourany, E.   Kouznetsov, V.   Kunne, R.   Lapik, A.   Sandri, P. Levi   Lleres, A.   Moricciani, D.   Mushkarenkov, A.   Nedorezov, V.   Nicoletti, L.   Perrin, C.   Rebreyend, D.   Renard, F.   Rudnev, N.   Russew, T.   Russo, G.   Schaerf, C.   Sperduto, M. -L.   Sutera, M. -C.   Turinge, A.  

    New experimental approach to study meson photoproduction in nuclei is discussed. It is based on the measurement of the recoil nucleon as a tagger for identification of the initial step of reaction. Propagation of mesons and nucleons within a nucleus is described by the Intra-Nuclear Cascade (INC) model. Simulations and preliminary experimental data for the deuteron target obtained at GRAAL are presented. (c) 2008 Elsevier B.V. All rights reserved.
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  • Systematic study of the features of the streamer discharge by means of pulse shape analysis

    Battistoni, G.   Candela, A.   De Mitri, I.   Denni, U.   Frani, A.   Guarino, F.   Nicoletti, L.   Patera, V.   Sciubba, A.  

    Several measurements were performed with a streamer tube on a muon beam in different geometric and operational configurations. The use of a wave form digitizer in recording streamer pulses produced by minimum ionizing particles allowed the discrimination between single and multiple streamer discharges. The rate of occurrence of multi-streamer pulses as a function of different parameters has been measured. Also, the dependence of charge and pulse shape on the angle of the track with respect to the wire were studied. The analysis of pulse shape can be used to improve the comprehension of the phenomenology of the streamer discharge, putting constraints on the existing models
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