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Imaging of Prostate Cancer Using C-11-Choline PET/Computed Tomography

Author:
Castellucci, Paolo  Ceci, Francesco  Fanti, Stefano  


Journal:
UROLOGIC CLINICS OF NORTH AMERICA


Issue Date:
2018


Abstract(summary):

This article reviews the role of C-11-choline-PET/computed tomography (CT) in patients with prostate cancer for diagnosis, staging, and restaging the disease in case of biochemical recurrence after primary treatment. The main application of this imaging procedure is restaging of the disease in case of biochemical recurrence. C-11-Choline-PET/CT proved its value for metastases-directed salvage therapies and for monitoring therapy response in castration-resistant patients. Prostate-specific antigen (PSA) and PSA kinetics values confirmed their correlation with C-11-choline PET/CT sensitivity. C-11-CholinePET/CT, despite low sensitivity to stage disease or in case of biochemical failure with low PSA levels, has an important impact on the management of patients with prostate cancer.


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