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Association Between Neutrophil to Lymphocyte Ratio and Severity of Coronary Artery Disease

Author:
Kaya, H.   Ertas, F.   Islamoglu, Y.   Kaya, Z.   Atilgan, Z. A.   Cil, H.   Caliskan, A.   Aydin, M.   Oylumlu, M.   Soydinc, M. S.  


Journal:
Clinical and Applied Thrombosis/Hemostasis


Issue Date:
2014


Abstract(summary):

The aim of this study is to investigate the association between neutrophil to lymphocyte ratio (NLR) and severity of coronary atherosclerosis. A total of 172 patients undergoing coronary angiography were included in the study. Control group consisted of patients with normal coronary arteries. Patients with coronary stenosis were divided into 2 groups by use of Gensini scores. The NLR was higher in severe atherosclerosis group compared with mild atherosclerosis and control groups (P < .001). In correlation analysis, NLR showed significant correlation with Gensini score. A cutoff value of 2.5 for NLR predicted severe atherosclerosis with a sensitivity and specificity of 62% and 69%, respectively. After multivariate analysis, high levels of NLR were independent predictors of severe atherosclerosis together with glucose and high-density lipoprotein. Our study suggests that the NLR is a predictor of severe atherosclerosis that may be useful for cardiac risk stratification in patients with coronary artery disease.


Page:
50-54


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