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X-Ray Computed Tomography Imaging of Breast Cancer by using Targeted Peptide-Labeled Bismuth Sulfide Nanoparticles

Author:
Dr. Joseph M. Kinsella   Rebecca E. Jimenez   Priya P. Karmali   Anthony M. Rush   V. Ramana Kotamraju   Prof. Nathan C. Gianneschi   Prof. Erkki Ruoslahti   Dr. Dwayne Stupack   Prof. Michael J. Sailor  


Journal:
Angewandte Chemie


Issue Date:
2011


Abstract(summary):

Thumbnail image of graphical abstract Eine verbesserte Visualisierung von Brustkrebs mit Röntgen-Computertomographie wird durch Verwendung von Bi2S3-Nanopartikeln von 10 nm Durchmesser erreicht, die mit einem tumorerkennenden Peptid (LyP-1, CGNKRTRGC) modifiziert waren. Gegenüber unmarkierten Nanopartikeln war die Anreicherung der Nanopartikel im Tumor um 260 % erhöht.


Page:
12308-12311


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