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Anti–tumor necrosis factor-alpha therapy with infliximab as an alternative to corticosteroids in the treatment of human leukocyte antigen b27–associated acute anterior uveitis

Author:
El-Shabrawi, Yosuf   Hermann, Josef  


Journal:
Ophthalmology


Issue Date:
2002


Abstract(summary):

To evaluate the potentials of infliximab, a mouse–human chimeric immunoglobulin G1 monoclonal antibody that binds both the soluble form and the membrane-bound precursor of tumor necrosis factor-α (TNF-α), thus inhibiting a broad range of biologic activities of TNF-α, in the therapy of patients with acute HLA B27–associated anterior uveitis.


Page:
2342-2346


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