An overview of copper radionuclides and production of Cu-61 by proton irradiation of Zn-nat at a medical cyclotron RID H-1769-2011

Author:

Rowshanfarzad, Pejman  Sabet, Mahsheed  Jahlian, Amir Reza  Kamalidehghan, Mohsen  

Journal:

APPLIED RADIATION AND ISOTOPES

Issue Date:

2006

Abstract(summary):

In this article, production methods and applications of copper radionuclides are overviewed with special attention toward Cu-61, due to its interesting nuclear properties. Selection of production parameters for Cu-61 including: appropriate nuclear reaction, proton beam energy, target thickness and targetry method are discussed for NRCAM 30 MeV medical cyclotron. Zn-64(p,alpha)Cu-61 was selected as the best reaction and Cu-61 was produced by 22 MeV proton bombardment of a 80 mu m thick natural zinc target. After 180 mu Ah irradiation, the resultant activity of Cu-61 was 6.006 Ci (12.015 mCi/mu Ah). The chemical separation method was easy, quick and efficient (> 95%) and yielded a no carrier added product with high chemical and radionuclidic purity (> 99%). Detailed comparison with previous production methods confirms that our results are superior to other reports published to date. (c) 2005 Elsevier Ltd. All rights reserved.

Page:

1563---1573